Avis NE, Ip E, Foley KLEvaluation of the Quality of Life After Cancer Survivors (QLACS) Scale for long-term cancer survivors in a sample of breast cancer survivors. Health Qual Life Outcomes 4: 92

Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Health and Quality of Life Outcomes (Impact Factor: 2.12). 02/2006; 4(1):92. DOI: 10.1186/1477-7525-4-92
Source: PubMed


This paper evaluates psychometric properties of a recently developed measure focusing on the health-related quality of life (HRQL) of long-term cancer survivors, the Quality of Life in Adult Survivors scale (QLACS), in a sample of breast cancer survivors. This represents an important area of study, given the large number of breast cancer patients surviving many years post diagnosis.
Analyses are based on an 8-year follow-up of a sample of breast cancer survivors who participated in an earlier study conducted in 1995. Participants were re-contacted in 2003 and those who were reachable and agreed to participate (n = 94) were surveyed using a variety of measures including the QLACS. Additional follow-up surveys were conducted 2 weeks and one year later. Psychometric tests of the QLACS included test-retest reliability, concurrent and retrospective validity, and responsiveness.
The QLACS domain and summary scores showed good test-retest reliability (all test-retest correlations were above .7) and high internal consistency. The Generic Summary Score showed convergent validity with other measures designed to assess generic HRQL. The Cancer-Specific Summary score exhibited divergent validity with generic HRQL measures, but not a cancer-related specific measure. The QLACS Cancer-Specific Summary Score demonstrated satisfactory predictive validity for factors that were previously shown to be correlated with HRQL. The QLACS generally demonstrated a high level of responsiveness to life changes.
The QLACS may serve as a useful measure for assessing HRQL among long-term breast cancer survivors that are not otherwise captured by generic measures or those specifically designed for newly diagnosed patients.

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    • "Seven scales (23 %) met the reliability criteria, that is, having both adequate internal consistency and temporal stability: ASEX [29], FSFI [30], Sexual Self-Schema Scale [31], and the sexual functioning subscales of the CARES [26], MRS [32], QLACS [33], and WHOQOL-100 [28]. "
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    • "The number of items and domains in the instruments ranged from 12-83 and 2-12, respectively. According to the QoL framework proposed by Ferrell et al., three of the identified disease-specific instruments (QOL-CS, QLACS, and QLI-CV) evaluated all four domains (physical, psychological, social, and spiritual) of QoL and included items consistent with survivor's concerns [20,24,25]. Other disease-specific instruments (EORTC QLQ-C30, EORTC QLQ-BR23, FACT-G, FACT-B, CARES-SF, and BIRS) included both physical and psychosocial domains [14-19,21,22], while FACIT-SP assessed only the spiritual aspect of QoL [23]. "
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    • "As at the time of data collection there was no consensus over the most appropriate measures of health outcome for long-term cancer survivors, health and well-being was assessed using 25 items from the National Health Interview Study (Hewitt and Rowland, 2002; Hewitt et al, 2003) adapted for the UK, where there were differences for language and terminology and incorporating two additional items from the Quality of Life after Cancer Scale (Avis et al, 2006) and two items on financial problems and debt. The questionnaire was piloted before use in the main survey. "
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