Article

A case of HHV-6 associated acute necrotizing encephalopathy with increase of CD56bright NKcells.

Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Scandinavian Journal of Infectious Diseases (impact factor: 1.72). 02/2006; 38(11-12):1122-5. DOI:10.1080/00365540600740520 pp.1122-5
Source: PubMed

ABSTRACT We describe a 15-month-old girl with acute necrotizing encephalopathy (ANE) associated with HHV-6. Inflammatory cytokines were elevated in the CSF and serum and the number of CD56bright NK cells was significantly increased in the peripheral blood. CD56bright NK cells may be involved in the pathogenesis of ANE by producing inflammatory cytokines.

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Keywords

15-month-old girl
 
ANE
 
CD56bright NK cells
 
CSF
 
Inflammatory cytokines
 
pathogenesis
 

Tomohiro Kubo