Hemophagocytic syndrome is a rare complication of acute Q fever. We reported the case of 26-year-old man with fever, chills, severe headache, non-productive cough and progressive thrombocytopenia. Bone marrow aspirate revealed hemophagocytosis. We discussed the differences among the three previous reported cases and the possible mechanisms of hemophagocytic syndrome.
"Bone marrow was examined both cytologically and histologically in this study because chronic C. burnetii infection in humans has been associated with bone marrow pathology such as ‘doughnut ring’ granulomas [21,22] and an acute hemophagocytic syndrome . While neither of these lesions were observed, results of the bone marrow analysis may be helpful as a reference range for this species given the paucity of baseline information on many free ranging pinnipeds. "
[Show abstract][Hide abstract] ABSTRACT: Background
The northern fur seal (Callorhinus ursinus) is an important cultural and nutritional resource for the Aleut community on St. Paul Island Alaska. In recent years, an increasing number of zoonotic pathogens have been identified in the population, but the public health significance of these findings is unknown. To determine the prevalence of Coxiella burnetii and Brucella spp. in northern fur seal tissues, eight tissue types from 50 subsistence-harvested fur seals were tested for bacterial DNA by real-time polymerase chain reaction.FindingsOf the 400 samples tested, only a single splenic sample was positive for Brucella spp. and the cycle threshold (ct) value was extremely high suggesting a low concentration of DNA within the tissue. C. burnetii DNA was not detected.Conclusions
Findings suggest that the risk of humans contracting brucellosis or Q fever from the consumption of harvested northern fur seals is low.
[Show abstract][Hide abstract] ABSTRACT: Oversize waveguide has recently been used successfully to develop a variable attenuator, directional coupler, phase shifter, and a duplexer at 330 Gc. Use of oversize waveguide results in lower loss components at millimeter and submillimeter wavelengths. Filter structures using quasioptical techniques in oversize waveguides are described in this paper.
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