A rapid screening battery to identify frontal dysfunction in patients with ALS

Department of Neurology, Penn State College of Medicine, Penn State Hershey Medical Center, Hershey, PA 17033, USA.
Neurology (Impact Factor: 8.3). 01/2007; 67(11):2070-2. DOI: 10.1212/01.wnl.0000247667.89251.43
Source: PubMed

ABSTRACT We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.

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