Article

Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha(1)-adrenoceptor antagonist.

Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennidai, Tsukuba, Ibaraki 305-8575, Japan.
American Journal of Ophthalmology (impact factor: 4.22). 02/2007; 143(1):150-1. DOI:10.1016/j.ajo.2006.07.046 pp.150-1
Source: PubMed

ABSTRACT To evaluate the incidence of Intraoperative Floppy Iris syndrome (IFIS) in relation to the usage of alpha(1)-adrenoceptor antagonists.
Prospective, interventional case series.
In 2,643 consecutive eyes of 1,968 patients undergoing cataract surgery, occurrence of IFIS and use of alpha(1) antagonists were recorded.
IFIS was observed in 29 eyes (1.1%) of 25 male patients, all of whom were receiving alpha(1) antagonists. In those receiving systemic tamsulosin, alpha(1A) selective antagonist, IFIS developed in 25 (43.1%) of 58 eyes. In those receiving systemic naftopidil, alpha(1A) and alpha(1D) antagonists, IFIS was found in 4 (19.0%) of 21 eyes. There was no case of IFIS in patients who received other systemic alpha(1) antagonists and in eyes treated with bunazosin eyedrops, a nonselective alpha(1) antagonist.
IFIS occurred in 1.1% of cases treated with systemic alpha(1A)-adrenoceptor antagonists for benign prostatic hypertrophy. Topical nonselective alpha(1) antagonist did not induce IFIS.

0 0
 · 
0 Bookmarks
 · 
21 Views
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

1,968 patients undergoing cataract surgery
 
2,643 consecutive eyes
 
alpha(1)-adrenoceptor antagonists
 
benign prostatic hypertrophy
 
bunazosin eyedrops
 
cases
 
eyes
 
interventional case series
 
Intraoperative Floppy Iris syndrome
 
nonselective alpha(1)
 
systemic alpha(1)
 
systemic alpha(1A)-adrenoceptor antagonists
 
Topical nonselective alpha(1)
 

Tetsuro Oshika