Pyridoxine (vitamin B6) therapy for premenstrual syndrome

Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Teheran, Tehrān, Iran
International Journal of Gynecology & Obstetrics (Impact Factor: 1.56). 02/2007; 96(1):43-4. DOI: 10.1016/j.ijgo.2006.09.014
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    ABSTRACT: Background: Helicanthus elastica (Desr.) Danser (Loranthaceae) is less-known Indian medicinal mistletoe growing commonly on mango trees as hemiparsites. It is used to prevent abortion, in vescical calculi and kidney affections. These groups of plants are medicinally important as they are potential sources of anticancer, immunomodulatory, hepatoprotective, antimicrobial and antioxidant molecules. Materials and Methods: In the current study whole plant of H. elastica growing on mango trees is collected and subjected for physicochemical and nutraceutical analysis aiding standard methodology. The total ethanolic extract was fingerprinted with HPLC-UV. Results: Parameters like moisture content, total ash, water-soluble ash, acid-insoluble ash, alcohol-soluble and water-soluble extractive, successive extractive values by cold and hot extraction, heavy metals like arsenic, lead, cadmium and mercury, total bacterial count, total fungal count, presence of enterobacteriaceae, Escherichia coli, Salmonella spp., Pseudomonas aeruginosa and Staphylococcus aureus were tested under the head physicochemical examination. Determination of carbohydrate, fat, protein and fiber, calorific value, vitamins like niacinamide, pyridoxine, riboflavin, thiamine and ascorbic acid, trace elements like iron and zinc were estimated. Conclusion: The physicochemical tests are used as parameters for routine analysis and quality control of the plant. The investigations revealed appreciable quantity of important vitamins and trace elements in the plant. The HPLC-UV fingerprint would be an efficient tool for the standardisation and quality control of the mistletoe extract.
    International Journal of Green Pharmacy 01/2014; 8(3):175-179. DOI:10.4103/0973-8258.140177
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    ABSTRACT: Premenstrual syndrome (PMS) can be defined as a recurrent disorder that occurs every month in the luteal phase of the menstrual cycle, and remits with the onset of menstruation. It is believed to affect up to 80% of women of the reproductive age group. PMS is characterized by a complex set of symptoms which include physical, psychological and behavioural changes of varying severity. This can interfere with the lives of the affected, as well as their interpersonal relationships. Physiological theories of the aetiology of PMS have lead to proposals for treatment. A wide range of therapeutic interventions have been advocated in the treatment of PMS, many of which have side effects. As symptoms of PMS can be chronic and long-term, special attention should be paid to the side-effects of pharmacological interventions. For this reason, alternative approaches may be recommended. In this article, the non-pharmacologic therapeutic approaches advocated for the treatment of PMS will be briefly reviewed to assess their efficacy. Available evidence up to 2010 on non-pharmacologic treatment of premenstrual syndrome will be considered.
    07/2011; 5(3):148-152. DOI:10.12968/ajmw.2011.5.3.148