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To die or not to die: a HAT trick.

LBME, CNRS and Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse, France.
Molecular Cell (Impact Factor: 14.46). 01/2007; 24(6):807-8. DOI: 10.1016/j.molcel.2006.12.005
Source: PubMed

ABSTRACT In this issue of Molecular Cell, two manuscripts (Sykes et al., 2006) propose that the decision to undergo apoptosis upon DNA damage is mediated through acetylation of p53 within its DNA-binding domain by MYST histone acetyltransferases.

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