Olanzapine-induced agranulocytosis in systemic lupus erythematosus: a case report.

Department of Psychiatry, Chang Gung Memorial Hospital, Chia Yi Shen 61344, Taiwan, R.O.C.
General Hospital Psychiatry (Impact Factor: 2.9). 01/2007; 29(1):75-7. DOI: 10.1016/j.genhosppsych.2006.10.011
Source: PubMed

ABSTRACT Systemic lupus erythematosus (SLE) patients may have psychiatric manifestations during the illness course. Psychotropic agents are indicated in treating these symptoms. Second-generation antipsychotics, such as risperidone, olanzapine and quetiapine, have been thought to be safer than clozapine with regard to the side effect of neutropenia or agranulocytosis. We report a case of SLE who developed agranulocytosis during the treatment with olanzapine for the SLE-related psychiatric symptoms.

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