Influence of gender on the etiology of mitral regurgitation

Servicio de Cardiología, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Revista Espa de Cardiologia (Impact Factor: 3.34). 12/2006; 59(12):1335-8. DOI: 10.1016/S1885-5857(07)60091-7
Source: PubMed

ABSTRACT Our aim was to investigate the prevalence of the different causes of severe mitral regurgitation and the influence of gender on that prevalence. We performed a prospective study of 272 consecutive patients with severe mitral regurgitation that had been detected echocardiographically. Their mean age was 70.2 (13.8) years, and 143 were women (52.6%). Atrial fibrillation was present in 52.9%, 72.7% presented with heart failure, and 21.0% with previous myocardial infarction. The most common etiological factor was rheumatic disease (in 26.5%), with the etiology being unclear in 32 patients (11.8%). Rheumatic disease was more frequent in women, at 35.7%, than in men, at 16.3%, whereas other etiologies were less frequent in women (P< .001). In all age groups, a rheumatic etiology was more frequent in women. Rheumatic heart disease remains the main cause of severe mitral regurgitation observed in women referred to hospitals similar to ours.

Download full-text


Available from: Miguel Angel García-Fernandez, Dec 22, 2014
  • [Show abstract] [Hide abstract]
    ABSTRACT: Gender-based outcome data in coronary artery bypass graft (CABG) surgery has been the focus of extensive research over the last two decades. Increased awareness in gender-specific health and advancements in scientific research have produced evidence that risk profiles vary between genders and alter operative mortality after CABG. Some of these data remain controversial, emphasizing the complexity of gender as an independent variable and questioning processes of care that are intimately associated with outcome. Although patient gender cannot be changed, understanding gender-specific risks and modifying surgical practice may be helpful in improving patient outcomes.
    European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery 02/2011; 40(3):715-21. DOI:10.1016/j.ejcts.2011.01.003 · 2.81 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: The paper is devoted to the problem of choosing the proper form of operators upon fuzzy sets for the purposes of labeling fuzzy images. The union and intersection operators are considered. Based on some general properties of partitions, a criteria for selecting such operators is proposed and different combinations of fuzzy properties in the labeling process are considered
    Fuzzy Information Processing Society, 1996. NAFIPS. 1996 Biennial Conference of the North American; 07/1996
  • [Show abstract] [Hide abstract]
    ABSTRACT: Purpose To describe the etiology and to document the course of severe mitral regurgitation (MR). Methods Prospective registry of 272 patients diagnosed with chronic severe MR in an echocardiographic study. Results Mean age was 70.2±13.8 years and 143 patients were women (53%). The most frequent causes of regurgitation were rheumatic disease (72 patients; 26%), ischemic etiology (58; 21%), valve prolapse (57; 21%), and dilated cardiomyopathy (49; 18%). A total of 43 patients (16%) died during follow-up (mean 0.9±0.3 years, total 2,785 patient-months): 30 from cardiac causes, 9 from non-cardiac causes, and 4 from unknown causes. Actuarial transplant-free survival was 87% at 6 months, and 81% at 1 year. Renal disease, previous stroke, ischemic etiology, and poor left ventricular ejection fraction were independent predictors of mortality. Conclusions Rheumatic disease is still the main cause of severe MR in Spain. Patients with severe MR have advanced age and present poor short-term prognosis.
    The International Journal of Cardiovascular Imaging 01/2009; 25(2):121-126. DOI:10.1007/s10554-008-9363-8 · 2.32 Impact Factor