Cervical mature teratoma 17 years after initial treatment of testicular teratocarcinoma: Report of a late relapse

Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Science, Tehran, Iran.
World Journal of Surgical Oncology (Impact Factor: 1.41). 02/2007; 5(1):1. DOI: 10.1186/1477-7819-5-1
Source: PubMed


Late relapses of testicular germ cell tumor are uncommon. We report a case of cervical mature teratoma appeared 17 years after treatment of testicular teratocarcinoma.
A 20-year-old patient underwent left sided orchiectomy followed by systemic therapy and retroperitoneal residual mass resection in 1989. He remained in complete remission for 200 months. In 2005 a huge left supraclavicular neck mass with extension to anterior mediastinum appeared. Radical surgical resection of the mass was performed and pathologic examination revealed mature teratoma.
This is one of the longest long-term reported intervals of a mature teratoma after treatment of a testicular nonseminoma germ cell tumor. This case emphasizes the necessity for follow up of testicular cancer throughout the patient's life.

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    • "A Medline search was made on all publications involving cervical teratomas occurring in adults yielded less than 50 such case reports. However, if we exclude those occurring in thyroid, base of skull and along the cervical spine, there were only 10 cases reported (Table 1) [2] [5] [6] [7] [8] [9] [10] [11] [12] [13]. The aetiology of the cervical neck teratomas remains unknown. "
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