Inducible cell death in plant immunity. Semin Cancer Biol

Department of Molecular Biology, University of Copenhagen, Øster Farimagsgade 2A, 1353 Copenhagen K, Denmark.
Seminars in Cancer Biology (Impact Factor: 9.33). 05/2007; 17(2):166-87. DOI: 10.1016/j.semcancer.2006.12.001
Source: PubMed

ABSTRACT Programmed cell death (PCD) occurs during vegetative and reproductive plant growth, as typified by autumnal leaf senescence and the terminal differentiation of the endosperm of cereals which provide our major source of food. PCD also occurs in response to environmental stress and pathogen attack, and these inducible PCD forms are intensively studied due their experimental tractability. In general, evidence exists for plant cell death pathways which have similarities to the apoptotic, autophagic and necrotic forms described in yeast and metazoans. Recent research aiming to understand these pathways and their molecular components in plants are reviewed here.

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    • "Dichos procesos tienen que ver con mecanismos propios de diferentes estados de la planta, como, por ejemplo, la muerte de células aleurónicas durante la germi- Figura 5. a) Micrografía del grano que muestra aleurona de las células del endospermo diferenciadas terminalmente llenas de almidón; b) células de xilema diferenciadas; c) senescencia de la hoja de arce. Fuente: [4] nación (figura 5a); procesos de diferenciación del xilema (figura 5b); la reproducción y el desarrollo floral; diferenciación sexual de plantas hermafroditas en angiospermas [25] y durante el desarrollo de procesos de senescencia (figura 5c), la cual comienza con disminución de la rapidez fotosintética, caracterizada por una participación muy activa de las vacuolas y procesos de autofagia [26] "
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    ABSTRACT: La comprensión de los mecanismos de defensa de las plantas permite generar conocimiento básico para la conservación y el uso de los recursos filogenéticos, así como para la seguridad alimentaria. Un mecanismo importante en la vida de las plantas es la muerte celular programada, una especie de suicidio celular, reacción hipersensitiva parecida a la apoptosis animal. Este proceso les permite a las plantas el desarrollo de múltiples cambios durante su ciclo biológico, como también la defensa frente al ataque de patógenos y combatir el estrés.
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    • "PTI affords basal defense to plants by perception of evolutionarily conserved PAMPs (Zhang and Zhou 2010). ETI is often activated through the direct or indirect recognition of the pathogen avirulence (avr) gene product with the corresponding resistance (R) gene product in a plant-pathogen interaction, and confers disease resistance to the plant, typically inducing the hypersensitive response (HR) (Morel and Dangl 1997; Hofius et al. 2007). HR is the rapid and localized cell death at the site of infection, thereby resulting in the restriction of pathogen spread (Heath 1998). "
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    ABSTRACT: KEY MESSAGE : TaHIR1 and TaHIR3 play positive roles in resistance to the stripe rust fungus via inducing HR and regulating defense-related genes, but are negatively regulated by various abiotic stimuli. Plant hypersensitive-induced reaction (HIR) genes are known to be associated with the hypersensitive response and disease defense. In wheat, two HIR genes, TaHIR1 and TaHIR3, have been identified and found to be up-regulated after infection with the stripe rust fungus. Here, we further determined their roles in defense against abiotic stresses and the stripe rust pathogen, Puccinia striiformis f. sp. tritici. TaHIR1 and TaHIR3 proteins were localized in the plasma membrane of tobacco cells. The expression of TaHIR1 and TaHIR3 was reduced by the environmental stimuli, including low temperature, drought, and high salinity stresses. In addition, the expression of TaHIR1 and TaHIR3 was down-regulated by exogenously applied ethrel and abscisic acid, whereas expression was not affected by treatments with salicylic acid and methyl jasmonate. Furthermore, barley stripe mosaic virus-induced gene silencing of TaHIR1 and TaHIR3 reduced resistance in wheat cultivar Suwon11 against an avirulent stripe rust pathotype CYR23 and area of necrotic cells neighboring the infection sites, and altered the expression levels of defense-related genes. These results suggest that TaHIR1 and TaHIR3 function positively in the incompatible interaction of wheat-stripe rust fungus, but exhibit negative transcriptional response to abiotic stresses.
    Plant Cell Reports 10/2012; 32(2). DOI:10.1007/s00299-012-1361-6 · 2.94 Impact Factor
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    • "c o m / l o c a t e / g e n e Bratton and Cohen, 2001; Jacobson et al., 1997), we have investigated the mechanism of PCD in plants. Studies on PCD could also open up opportunities for improving biotic and abiotic stress tolerance in plants (Greenberg, 1997; Hofius et al., 2007; Jones, 2001) also may provide new avenues for manipulating cell death in both plant and animal systems (Collazo et al., 2006; Doyle et al., 2010; Green and Reed, 1998; Jacobson et al., 1997; Jan et al., 2008; Kerr et al., 1972; Pennell and Lamb, 1997; Peters and chin, 2005; Reape and McCabe, 2010; Vaux and Korsmeyer, 1999). "
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    ABSTRACT: The event of bamboo flowering and subsequent death of bamboo cells, a rare phenomenon is an interesting model to study gene expression/function in the context of the programmed cell death (PCD) in plant. To identify genes involved in autolytic cell death in bamboo (Bambusa arundinacea/Bambusa bambos Voss), a suppressive subtractive cDNA hybridization (SSH) was performed between cDNA isolated from control (healthy), as driver and test internodal tissue (45days after setting of seeds), as tester. In-silico data revealed that 82% of total ESTs (231) were non-significant (unidentified proteins) while remaining ESTs were classified as protein with known/predicted function/s. Among these, net distribution and differential expression patterns of 11 important B. arundinacea PCD specific ESTs were studied using RNA slot-blot, qRT-PCR and semi-quantitative RT. In-situ localization of mRNA-transcripts for selected bamboo PCD-specific ESTs namely V2Ba48 (Aldehyde dehydrogenase 2) and V2Ba19 (Glycogen phosphorylase) were detected using digoxigenin-labeled corresponding anti-sense RNA probes employing Confocal Laser Scanning Microscope (CLSM). Differential expression-kinetics of the aforementioned genes were confirmed during the progress of PCD after setting of seeds. Global appearance of V2Ba48, V2Ba19, V2Ba95 (Ubiquitin thioesterase) and V2Ba89 (Nebulin isoform 2) genes were identified in monocot (Oryza sativa) and dicots (Arabidopsis thaliana and Nicotiana tabacum). This is the first report on systematic analysis of genes involved in death of bamboo cells that may provide critical information regarding key metabolic/regulatory genes involved in plant PCD.
    Gene 02/2012; 497(2):243-8. DOI:10.1016/j.gene.2012.01.018 · 2.08 Impact Factor
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