Beneficial Effects of the Antiglutamatergic Agent Riluzole in a Patient Diagnosed With Trichotillomania

The Journal of Clinical Psychiatry (Impact Factor: 5.14). 02/2007; 68(1):170-1. DOI: 10.4088/JCP.v68n0123f
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    ABSTRACT: Trichotillomania, or chronic hairpulling, is a common condition that affects primarily women. The disorder can cause significant psychosocial impairment and is associated with elevated rates of psychiatric comorbidity. In this article, the phenomenology, etiology, assessment, and treatment of the disorder are discussed.
    Psychiatric Clinics of North America 09/2014; DOI:10.1016/j.psc.2014.05.005 · 2.13 Impact Factor
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    ABSTRACT: Pathological Gambling (PG) is characterized by "the failure to resist gambling impulses despite severe personal, family or occupational consequences". PG estimated prevalence ranges between 0.4% and 3.4% within the adult population. PG seems to be more common in patients with Parkinson's disease (PD) than in the general population. In the past few years, PG has been reported as a side effect of dopamine agonist (DA) therapy used in PD. This association has aroused great interest for the dramatic impact PG has on patients' quality of life. Management of PG in patients with PD could be demanding. It is based on patient and caregiver education, modification of dopamine replacement therapy, and in some cases psychoactive drug administration. This review describes possible pathogenesis of PG associated with DA therapy, available pharmacological treatments and management approaches that may increase the likelihood of satisfactory treatment outcomes in PD patients.
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    ABSTRACT: This article provides a brief review of the current available data concerning present treatment and potential new treatment advances for pediatric anxiety disorders, such as generalized anxiety disorder, separation anxiety disorder, social phobia, obsessive-compulsive disorder, and posttraumatic stress disorder. Disorder-specific treatment methods and innovations, particularly computer-assisted methods of delivery for cognitive behavioral therapy (CBT) will be reviewed. Additionally, the paper will discuss novel psychopharmacological compounds (e.g., d-cycloserine, riluzole, memantine, and anticonvulsant medications). Available evidence for the efficacy of novel medication strategies in adult studies and implications for their use in pediatrics will be discussed.
    Annals of the New York Academy of Sciences 11/2013; 1304(1):52-61. DOI:10.1111/nyas.12318 · 4.31 Impact Factor