Coeliac disease and risk of schizophrenia and other psychosis: A general population cohort study
ABSTRACT Several case reports and a recent study on coeliac disease (CD) and family history of schizophrenia indicate a link between CD and schizophrenia. The objective of our study was to determine the risk of non-affective psychosis in patients with CD in a national general population cohort.
We identified 14,003 individuals with a diagnosis of CD in the Swedish national inpatient register between 1973 and 2003. From the population register, Statistics Sweden then identified five reference individuals matched for age and calendar year at diagnosis, gender and county (n=68,125). Only individuals with more than one year of follow-up after the CD diagnosis was first recorded or a corresponding date in reference individuals were included in the analyses. The risk of subsequent non-affective psychosis in individuals with CD was estimated by Cox regression.
CD was associated with a statistically significant increased risk of any non-affective psychosis (hazard ratio (HR)=1.55; 95% CI=1.16-2.06; p=0.003) (65 positive events in 14,003 individuals with CD and 216 positive events in 68,125 individuals without CD); this increased risk was largely due to the association with non-schizophrenic non-affective psychosis (HR=1.61; 95% CI=1.19-2.20; p=0.002: 56 positive events in individuals with CD and 180 among reference individuals). There was no statistically significant association with subsequent schizophrenia (HR=1.43; 95%=0.77-2.67; p=0.261: 14 positive events in individuals with CD and 50 among reference individuals).
Individuals with CD may be at increased risk of non-affective psychosis.
Conference Paper: DFT for improving the testability of parametric resistor faults[Show abstract] [Hide abstract]
ABSTRACT: This paper describes a test approach for a strain gauge measurement circuit. The test method is based on the analysis of equivalent faults extracted before the test solution conceptualization stage. Experimental results obtained demonstrate the effectiveness and validity of the approach.ASIC, 2003. Proceedings. 5th International Conference on; 11/2003
- [Show abstract] [Hide abstract]
ABSTRACT: Background: The twelve month stability of a diagnosis of schizophrenia after a first episode of psychosis is higher in men than in women. Purpose: To explore confounding conditions that exist in women. Method and Results: Review of recent literature on psychosis associated with starvation, diet aids, immune disorders, steroid use, estrogen withdrawal, thyroid conditions, abuse of domestic solvents, Turner Syndrome, depression, sleep deprivation, and posttraumatic stress. Conclusion: Clinicians need to screen for conditions prevalent in women that can induce psychosis and mimic schizophrenia. This will diminish erroneous diagnosis and inappropriate treatmentClinical Schizophrenia & Related Psychoses 10/2007; 1(3):77-82. DOI:10.3371/CSRP.1.3.8