Article

What is quality of life in children with bone sarcoma?

Stony Brook University Hospital, Stony Brook, NY, USA.
Clinical Orthopaedics and Related Research (impact factor: 2.53). 07/2007; 459:34-9. DOI:10.1097/BLO.0b013e31804f545d pp.34-9
Source: PubMed

ABSTRACT Quality of life measures have neglected to include a critical self-assessment component in pediatric sarcoma patients. Our report shows how children rate their own quality of life and how that varies over time after surgery. Using the Pediatric Outcomes Data Collection Instrument, quality of life data was prospectively collected and combined with a retrospective review of clinical parameters on 43 children with primary bone sarcoma, with an average followup of 3 years. Children reported good yet variable scores in five of the six domains. Lower scores were noted in the Sports/Physical Functioning domain, particularly in the first 12 months after surgery, with improvement seen up to 24 months after surgery. Tumor specific factors such as size larger than 8 cm and lower extremity location were negative predictors for Sports/Physical Functioning. The only demographic factor that predicted perceived quality of life scores was gender, with girls reporting lower scores in Sports/Physical Functioning, Pain/Comfort, and Global Functioning domains. The Pediatric Outcomes Data Collection Instrument gives discriminatory detailed textured evaluation of the outcome of children treated for skeletal sarcoma. Further development of quality of life measures is needed to allow its use in treatment selection.

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Keywords

24 months
 
43 children
 
average followup
 
children
 
children rate
 
critical self-assessment component
 
first 12 months
 
Global Functioning domains
 
life data
 
life measures
 
life scores
 
lower extremity location
 
Pediatric Outcomes Data Collection Instrument
 
pediatric sarcoma patients
 
primary bone sarcoma
 
retrospective review
 
six domains
 
size larger
 
Sports/Physical Functioning domain
 
textured evaluation
 

Jenny M Frances