An unusual vulval lesion in an HIV-infected woman

Whittall Street Clinic, Birmingham B4 6DH, UK.
International Journal of STD & AIDS (Impact Factor: 1.05). 04/2007; 18(3):218-9. DOI: 10.1258/095646207780132361
Source: PubMed


This is the case of a black African woman who presented with three distinct episodes of herpes simplex virus (HSV) infection unresponsive to first-line therapy. Clinical and virological resistance to aciclovir therapy was demonstrated, and although the first two episodes manifested as the deep ulceration often associated with HIV/HSV coinfection, the third was an atypical hypertrophic lesion. This is despite her CD4 count being persistently above 300 and there being no previous diagnosis of AIDS.

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