Clinicians' guide to new tools and features of PubMed.

Division of Primary Care Internal Medicine, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Mayo Clinic Proceedings (Impact Factor: 6.26). 05/2007; 82(4):480-3; quiz 484. DOI: 10.4065/82.4.480
Source: PubMed


Practicing clinicians need to have the skills required to obtain up- to-date medical information to address both the expansion of scientific knowledge and patients' increasing use of the Internet. PubMed ( allows clinicians free access to the largest biomedical resource available. This article is the third in a Mayo Clinic Proceedings series designed specifically to help clinicians unlock the tools and information available through this valuable resource.

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    ABSTRACT: PubMed is a freely accessible database specialized in health sciences, with more than 19 million bibliographical references. Because of its thematic coverage, including journals (more than 80 related to rheumatology), biomedical terminology and constant updating, consultation of this database by rheumatologists requiring information is a necessity. PubMed not only allows simple searches but also runs more complex queries through search functions for fields, MeSH terms or limits. The results of these searches can be saved with different tools and displayed in distinct formats. This article provides an overview of the major utilities of PubMed, accompanied by examples, and some recommendations on how to make searches more effective.
    Seminarios de la Fundación Española de Reumatología 04/2010; 11(2). DOI:10.1016/j.semreu.2010.02.005
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    ABSTRACT: There is a growing consensus in the clinical literature about the importance of establishing and utilizing empirically supported treatments (ESTs). A number of established criteria for determining the efficacy and effectiveness levels of treatments are reviewed, and an argument is put forth that the research paradigm of large-scale group comparison designs may not be the best conceptual fit for studying psychophysiological phenomena. Clinical psychophysiology employs reinforcing successive approximations of functional abilities: a model closer in nature to operant conditioning, physical rehabilitation, and education than the standard pharmacological model. Single-case designs have a long, well-accepted history in scientific disciplines and require resources that allow practice-level clinicians to make meaningful contributions to the scientific literature. They also have a clear role in the establishment of a treatment as an EST. A discussion of the logic, structure, and techniques of single-case design is presented in sufficient detail to actively construct publishable studies. The adaptive nature of this technique makes it possible to address a wide range of potential psychophysiological research questions, along with barriers to utilization, including ethical considerations. Techniques are presented to allow researchers to examine treatment efficacy and effectiveness as well as isolate components of treatment to determine the most powerful elements of a clinical intervention.
    Journal of Neurotherapy 02/2011; 15(1-1):18-34. DOI:10.1080/10874208.2011.545762