Paratesticular rhabdomyoma in a young adult: case study and review of the literature

Childrens Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
Journal of Pediatric Surgery (Impact Factor: 1.39). 05/2007; 42(4):E5-7. DOI: 10.1016/j.jpedsurg.2007.01.057
Source: PubMed


Paratesticular rhabdomyoma is a rare benign tumor, which usually presents as a painless mass in the scrotum or groin. We report the first case of a locally invasive paratesticular rhabdomyoma in a 17-year-old male teenager who presented with chronic scrotal pain. We further review the current literature of this rare tumor.

7 Reads
  • Source
    • "In humans, rhabdomyomas account for only 2% of all skeletal muscle tumors (Weiss and Goldblum 2001). Most extracardiac rhabdomyomas are located in the head and neck region (Hansen and Katenkamp 2005), but a genital type of rhabdomyoma has been reported in the paratestis of a young adult (Davies et al. 2007). In mice, the pathogenesis of rhabdomyomas was studied by Meikle et al. (2005). "
    [Show abstract] [Hide abstract]
    ABSTRACT: An eight-week-old male Sprague-Dawley (SD) rat showed signs of emaciation, and masses were found in the subcutis around the cervical and thoracic regions. At necropsy, a multilobular mass, 2.2 x 1.8 x 2.0 cm in size, had grown from the left neck into the thoracic cavity. On a cutting surface, masses were firm and whitish to tan, with necrotic and hemorrhagic plaques. Microscopically, masses were composed of multiple nodules of tumor cells that were incompletely encapsulated with fibrous connective tissue. The tumor cells exhibited varied forms, from spindle to globoid shapes with minimal to abundant eosinophilic cytoplasm, and appeared as large, multinucleated cells; many of the tumor cells were vacuolated. Histochemistry results revealed that tumor cells exhibited some cross-striation in the cytoplasm using PTAH staining. There were some multinuclear tumor cells with vacuoles located around the nuclei, and these vacuoles showed reddish staining by the periodic acid Schiff (PAS) method. Immunohistochemical staining also expressed intense granular cytoplasmic staining for desmin and myoglobin, with highly positive staining for PCNA, whereas alpha-smooth muscle actin (alpha-SMA) was negative. Based on the pathology results, a spontaneous rhabdomyosarcoma with pleomorphic type was diagnosed in a young SD rat.
    Toxicologic Pathology 10/2008; 36(6):866-70. DOI:10.1177/0192623308323623 · 2.14 Impact Factor
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: Objectives To describe female sexual behavior in recent decades in regard to the beginning of sexual activity (AS), coital frequency and sexual satisfaction according to age group and educational level. Methods This is a cross-section, observational, descriptive study in white female population> 18 years with convenience sampling and sample size of 587 patients. Results were compared with a previous paper published by the same author (1988) with 601 women. Results The average age was 37years. Most frequently the patients had a technical or professional education. They had an average of 1.3 + / -1.2 children. Mean age at initiation of sexual activity was 18years. For most of interviewed woman the onset sexual activity was pleasant, 57% had premarital intercourse and 41% took the first step for a sexual intercourse. 91.6% have orgasms, 45% simulate orgasm �occasionally� and 19% had extramarital sexual activity: The average age of this group is 36years and 86% have superior education. There was an overall satisfaction in 75% of the cases, and 82% describe their partner as �good�. Conclusions: Women in the last three generations show an earlier beginning of sexual activity, often taking the lead in relationships and intercourse; they are satisfied with their partners and sexual activity. This is reflected in greater orgasmic capacity, higher education level, a greater ability to enjoy sex, and a greater possibility of having extramarital intercourse. Yet, a high percentage fake orgasms occasionally. Objetivos. Describir el comportamiento sexual femenino en las últimas décadas en inicio de actividad sexual (AS), frecuencia coital y satisfacción sexual según grupo etáreo y nivel educativo. Materiles y Métodos. Estudio observacional descriptivo de corte transversal, población blanco mujeres >18a; muestreo por conveniencia, tamaño de muestra 587 y un paralelo final con estudio similar del autor (1988) con 601 mujeres. Análisis de Resultados La población tenía promedio de edad 37a, principalmente estudios superiores, promedio de hijos 1.3 +/-1.2. La moda de inicio de AS fue 18a. Para la mayoría el inicio de AS fue agradable; 57% tuvo coito prematrimonial y 41% toma la iniciativa sexual. El 91.6% presentan orgasmos. El 45% simulan orgasmo �ocasionalmente�. El 19% tiene AS extramatrimonial: el promedio de edad de ellas es 36a y 86% tienen estudios superiores. Hubo 75% de satisfacción general con su AS y 82% califican a su pareja como �buena�. Conclusiones. Al comparar los datos de las tres últimas generaciones las mujeres comienzan más temprano su AS, toman la iniciativa frecuentemente, están satisfechas con sus parejas y su AS, esto se refleja en mayor capacidad orgásmica. A mayor educación, mayor capacidad para disfrutar la sexualidad, mayor posibilidad de una AS extramatrimonial y aún, un alto porcentaje finge el orgasmo ocasionalmente.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Extracardiac rhabdomyoma is a very rare neoplasm of skeletal muscle differentiation. The case history reported below refers to an unusual and rare case of endobronchial adult extracardiac rhabdomyoma in a patient with recurrent episodes of dyspnea on exertion, diagnosed and treated unsuccessfully as exercise-induced asthma. The report provides a brief review of the literature on this entity. Histopathologic and immunocytochemical analysis revealed a fetal rhabdomyoma.
    Journal of Bronchology 10/2008; 15(4):262-263. DOI:10.1097/LBR.0b013e31818550c6
Show more