Article

Local recurrence of stage 1 and 2 breast cancer after skin-sparing mastectomy and immediate breast reconstruction in a 15-year series.

Department of Plastic Surgery, Helsinki University Central Hospital, P.O. Box 266, FI-00029 HUS, Helsinki, Finland.
European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology (impact factor: 2.56). 01/2008; 33(10):1142-5. DOI:10.1016/j.ejso.2007.03.022 pp.1142-5
Source: PubMed

ABSTRACT Since the introduction of skin-sparing mastectomy (SSM) in 1991 concerns on local control and recurrence rates have been discussed in the literature. The aim of this study is to examine in particular incidence of local recurrence in a 15-year consecutive series of breast cancer patients having undergone SSM and immediate breast reconstruction (IBR) at a single population-based institution.
One hundred and forty-six consecutive patients with either stage 1 or 2 breast cancer who underwent SSM followed by IBR from 1992 to 2006 were included in this study. A retrospective review of patient records was conducted.
During a mean follow-up time of 51 months, four local recurrences of the native breast skin were accounted for. In addition, three regional lymph node recurrences and four systemic recurrences took place. All of the local and regional recurrences were handled by salvage surgery followed by adjuvant oncological therapies. During a mean follow-up of 35 months after the detection and treatment of the locoregional recurrences none of the patients developed new recurrences.
Our present study concludes that SSM followed by IBR seems oncologically sound procedure for stage 1 and 2 breast cancer patients. In addition, local recurrences and regional lymph node recurrences are not always associated with systemic relapse.

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    BMC Cancer 01/2010; 10:171. · 3.01 Impact Factor
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Keywords

15-year consecutive series
 
2 breast cancer
 
2 breast cancer patients
 
adjuvant oncological therapies
 
breast cancer patients
 
consecutive patients
 
immediate breast reconstruction
 
local control
 
local recurrences
 
locoregional recurrences
 
mean follow-up time
 
native breast skin
 
new recurrences
 
oncologically sound procedure
 
regional lymph node recurrences
 
regional recurrences
 
single population-based institution
 
stage 1
 
systemic recurrences
 
systemic relapse