Article

Ocular drug delivery: Molecules, cells, and genes

Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison 53705-3611, USA.
Canadian Journal of Ophthalmology (Impact Factor: 1.3). 07/2007; 42(3):447-54. DOI: 10.3129/i07-049
Source: PubMed

ABSTRACT Recent advances in molecular cell biology have led to the exploration of new therapies based on molecules, cells, and genes to treat a variety of ocular disorders. In this review, we present the current state of knowledge pertaining to the development of different delivery systems to mediate safe and long-lived therapies, with an emphasis on gene therapy. The advantages and limitations of these delivery and therapeutic methods are also discussed.

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