Quality of life (QoL) in relation to disease severity in Brazilian Parkinson's patients as measured using the WHOQOL-BREF.

Laboratory of Physical Activity and Aging, Department of Physical Education, Sao Paulo State University (UNESP), Avenida 24 A, 1515 Bela Vista, Rio Claro, CEP 13506-900, SP, Brazil.
Archives of Gerontology and Geriatrics (Impact Factor: 1.53). 03/2008; 46(2):147-60. DOI: 10.1016/j.archger.2007.03.007
Source: PubMed

ABSTRACT This study aimed at evaluating and describing the QoL and its association with the severity of disease among Brazilian Parkinson's disease (PD) patients. In this cross-sectional study 68 PD patients were interviewed using the World Health Organization Quality of Life Instrument Short Form (WHOQOL-BREF) and the Hoehn-Yahr (HY) scale. Analysis of variance, chi(2), Kruskal-Wallis and Mann-Whitney U-tests, Spearman and Cronbach reliability coefficients were used to analyze the data. The results indicate: (1) physical capacity was the domain that showed the most deterioration; (2) severity of PD is associated with QoL measured by WHOQOL-BREF; (3) overall QoL, working capacity, activities of daily living (ADL) and self-esteem are affected in both transitional periods in the progression of PD (mild to moderate and moderate to advanced). Satisfaction with general health, pain, energy, positive feelings, personal relationship and satisfaction with home are affected in the first period of transition while mobility, body image, sexual activity and access to information are affected in the second. This study mainly shows specific facets that are affected depending on the specific periods of PD progression, which can help to understand the impact of the disease, the effectiveness of care, and the demand for health care resources.

  • [Show abstract] [Hide abstract]
    ABSTRACT: The Leeds Behçet's disease quality-of-life (BD-QoL) questionnaire is a specific and valid measure which is applied in English-speaking patients. We conducted Persian adaptation of BD-QoL questionnaire. Between June and December 2012, 220 Iranian patients fulfilling International Study Group criteria for the diagnosis of BD attending the rheumatology clinics at Tehran University of Medical Sciences were enrolled. Bilingual translators undertook the forward translation and cross-cultural adaptation of the BD-QoL questionnaire. Back-translation was conducted, and this version was sent to the designer of the questionnaire and revised accordingly. SF-36 health survey, Iranian Behçet's disease dynamic activity measure (IBDDAM), and Behçet's Disease Current Activity Form (BDCAF) were other administered measures. The Varimax rotation method with Kaiser normalization defined 5 factors with eigenvalues greater than 1.0. Studied cases were comprised of 118 males (53.6 %) and 102 females (46.4 %). Mean age of the patients was 38.3 ± 11.3 years (range 16-73). The mean BD-QoL score was 10.3 ± 8.8. Test-retest reliability was high, and two time points were significantly correlated (Spearman's correlation coefficient of 0.75-0.84). Cronbach's α coefficient of 0.949 demonstrated the excellent internal consistency. These factors cumulatively explained 58.74 % of total variance. The ratio of first to second eigenvalue was 7.08, which underlined the undimensionality. The results revealed adapted BD-QoL scores had significant correlation with IBDDAM (correlation coefficient = 0.19, P value = 0.005) and BDCAF (correlation coefficient = 0.21, P value = 0.002). Conversely, no significant correlation between BD-QoL and SF-36 results was detected (P value = 0.078). The Persian version of BD-QoL was shown to be unidimensional, highly reliable, and adequate construct validity.
    Rheumatology International 09/2014; 35(4). DOI:10.1007/s00296-014-3128-6 · 1.63 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: This paper presents an algorithm for efficiently designing, fabricating, and constructing the mechanical, electrical, and plumbing (MEP) systems for buildings. MEP facility construction presents numerous challenges related to its complexity, space limitations, and interference with other trades working in confined areas. Besides, schedule delays can easily be caused by the uncontrolled delivery schedule of the components. This research provides a rational planning algorithm which packages large and complex MEP systems into several smaller fabricated components using spatial planning algorithms to increase the efficiency of the installation process, create a safer work environment, improve construction quality and productivity, reduce construction cycle time, and minimize cost. Furthermore, the technique is verified and validated by three experts and a case study is presented to demonstrate the effectiveness of this algorithm.
    Automation in Construction 11/2011; 20(7):837-863. DOI:10.1016/j.autcon.2011.03.002 · 1.82 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: A study was conducted to explore the effects of Parkinson's disease on people's social interactions. An exploratory qualitative design was used. Participants were a purposive sample of 10 people with Parkinson's disease who were attending a hospital outpatients' neurology clinic. Data were collected by semi-structured in-depth interviews. All interviews were transcribed and analysed by using conventional content analysis to explore the participants' experiences and perceptions on social interactions, using the central question 'what effect does Parkinson's disease have on people's social interactions?' Analysis revealed that Parkinson's disease affected social interactions by disrupting social connectedness. Social connectedness was disrupted by a number of factors, including 'progressive physical disability, mood disturbances, shrinking of social activities and secluding oneself'. Older adults with Parkinson's disease therefore face a number of challenges to remaining socially connected. It appears that disrupted social connectedness is one of the negative consequences of living with Parkinson's.
    British journal of community nursing 03/2014; 19(3):136-141. DOI:10.12968/bjcn.2014.19.3.136