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Antioxidant activity of Erica arborea.

Canakkale Onsekiz Mart University, Faculty of Science and Arts, Department of Chemistry, Canakkale 17020, Turkey.
Fitoterapia (Impact Factor: 2.23). 01/2008; 78(7-8):571-3. DOI:10.1016/j.fitote.2007.03.024
Source: PubMed

ABSTRACT The antioxidant properties of the methanol extract of leaves and flowers of Erica arborea and the ethyl acetate, butanol and water soluble fractions were investigated. The ethyl acetate extract was found to be the richest for phenolic and flavonoid content which showed the highest antioxidant activity.

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    ABSTRACT: AIM: The present study was carried out to evaluate the antioxidant and anti-inflammatory capacity, and acute toxicity of Moroccan Erica arborea leaves. METHODS: Antioxidant capacity was assessed by diphenyle-picryl-hydrazyl (DPPH), phosphomolybdate (PPM) and ferric reducing antioxidant power (FRAP) tests and anti-inflammatory capacity was evaluated by hind paw oedema model using carrageenan-induced inflammation in rat. The acute toxicity was evaluated using mice. RESULTS: Acute toxicity of ethanolic extract of E. arborea showed no sign of toxicity at dose of 5g/kg B.W. Our extracts have important antioxidant properties. The efficient concentration of the ethanolic extract (10.22μg/ml) required for decreasing initial DPPH concentration by 50% was comparable to that of standard solution butyl-hydroxy-toluene (BHT) (8.87μg/ml). The administration of ethanolic extract at doses of 200 and 400mg/kg B.W. was able to prevent plantar oedema and exhibited a significant inhibition against carrageenan-induced inflammation when compared to the control group (NaCl 0.9%) but comparable to those of diclofenac (reference drug). CONCLUSIONS: Our results show that the leaves of E. arborea may contain some bioactive compounds which are responsible for the antioxidant and anti-inflammatory activities observed here. Our finding may indicate the possibility of using the extracts of this plant to prevent the antioxidant and inflammatory processes.
    Pathologie Biologie 05/2013; · 1.67 Impact Factor
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    ABSTRACT: Background and the purpose of the study: Erica arborea L. (Ericaceae) has been used in Turkey folk medicine as a diuretic, urinary antiseptic and laxative. However, its other pharmacological effects have not been yet elucidated clearly. The aim of this study was to investigate analgesic effects of its methanolic (MeOH) extract in mice using formalin test, as a model of tonic inflammatory pain. Methods: The MeOH extract of aerial parts and its fractions (20, 40, 60, 80 and 100% MeOH in water) were prepared by maceration and solid phase extraction method respectively. Effects of the MeOH extract (10, 20 and 30 mg/kg, i.p.) and different fractions (5 mg/kg, i.p.) were compared with analgesic effects of the morphine (10 mg/kg, i.p.) and indomethacine (5 mg/kg, i.p.) as standard analgesic drugs. Results and major conclusion: Results showed that the MeOH extract of E. arborea (10 mg/kg, i.p.) similar to the morphine (10 mg/kg, i.p.) and indomethacen (5 mg/kg, i.p.) decreased formalin-induced paw licking time,. Among the prepared-fractions of the MeOH extract, only fraction of 20% (5 mg/kg, i.p.) caused significant decrease in paw licking behavior. Moreover, the MeOH extract (10 mg/kg, i.p.) did not produce any motor deficit effects in rotarod test. From the results it may be concluded that the MeOH extract and faction of 20% of E. arborea have a good analgesic effects in formalin test. INTRODUCTION The Erica arborea L. (Ericacea) is a Turkish endemic species which is distributed in the Mediterranean and Anatolian regions and is also native to a number of other countries in Africa, Temperate Asia and Europe (1). This evergreen shrub or small tree is known as funda, tree heath or briar root in Turkey, and its leaves and flowers have been used as diuretic, urinary antiseptic, diet tea and laxative (2-3). It also has been shown that different extracts of leaves and flowers of E. arborea have considerable antioxidant effects (4). Also isolation of some new flavonoide and phenylethanoide glycosides and their antioxidant properties have been reported (5). There are repots about the anti-inflammatory and antinociceptive activity of the ethyl acetate extract of E. arborea in PGE 2 -induced hind paw edema model and p-benzoquinone-induced abdominal constriction test (6). Analgesic effects of the MeOH extract of this plant in hot plate test has also been reported (7). In the present study, analgesic effects of the MeOH extract and fractions obtained from E. arborea aerial parts were investigated in mice by using formalin test, as a model of chronic inflammatory pain.
    05/2012;
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    ABSTRACT: Aqueous extractions from two species of Erica consumed as infusions in several countries to heal ailments were investigated for their phenolic and flavonoid con-tents, along with antioxidant capacity and radical scavenging capacity using total antioxidant activity, ferric-reducing antioxidant power, reducing power, 1,1-diphenyl-2-picrylhydrazyl and 2-2'-azino-bis(3 ethylbenzothiazoline-6-sulfonic acid) radicals, respectively. Antioxidant properties and total phenolic content dif-fered significantly among these plants. Aqueous extracts of leaves possessed, on average, the highest antioxidant capacity and phenolic content (34.09 10.81 mg ascorbic acid equivalent/g dry weight and 30.59 10.19 mg gallic acid equivalent/ g dry weight, respectively) of all three plant parts. A significant correlation (r 2 = 0.952) between antioxidant capacity and total phenolic content was found, indicating that phenolic compounds are the major contributors to the antioxidant properties of these plants. Upon application of hierarchical cluster analysis to the results obtained, leaves with flowers were grouped in one cluster, whereas branches remained in another cluster, showing little interference from the collec-tion site or species factors.
    Journal of Food Quality 09/2012; 35:307-314. · 0.76 Impact Factor

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