Article

Antioxidant activity of Erica arborea.

Canakkale Onsekiz Mart University, Faculty of Science and Arts, Department of Chemistry, Canakkale 17020, Turkey.
Fitoterapia (Impact Factor: 2.23). 01/2008; 78(7-8):571-3. DOI: 10.1016/j.fitote.2007.03.024
Source: PubMed

ABSTRACT The antioxidant properties of the methanol extract of leaves and flowers of Erica arborea and the ethyl acetate, butanol and water soluble fractions were investigated. The ethyl acetate extract was found to be the richest for phenolic and flavonoid content which showed the highest antioxidant activity.

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    ABSTRACT: Aqueous extractions from two species of Erica consumed as infusions in several countries to heal ailments were investigated for their phenolic and flavonoid con-tents, along with antioxidant capacity and radical scavenging capacity using total antioxidant activity, ferric-reducing antioxidant power, reducing power, 1,1-diphenyl-2-picrylhydrazyl and 2-2'-azino-bis(3 ethylbenzothiazoline-6-sulfonic acid) radicals, respectively. Antioxidant properties and total phenolic content dif-fered significantly among these plants. Aqueous extracts of leaves possessed, on average, the highest antioxidant capacity and phenolic content (34.09 10.81 mg ascorbic acid equivalent/g dry weight and 30.59 10.19 mg gallic acid equivalent/ g dry weight, respectively) of all three plant parts. A significant correlation (r 2 = 0.952) between antioxidant capacity and total phenolic content was found, indicating that phenolic compounds are the major contributors to the antioxidant properties of these plants. Upon application of hierarchical cluster analysis to the results obtained, leaves with flowers were grouped in one cluster, whereas branches remained in another cluster, showing little interference from the collec-tion site or species factors.
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    ABSTRACT: AIM: The present study was carried out to evaluate the antioxidant and anti-inflammatory capacity, and acute toxicity of Moroccan Erica arborea leaves. METHODS: Antioxidant capacity was assessed by diphenyle-picryl-hydrazyl (DPPH), phosphomolybdate (PPM) and ferric reducing antioxidant power (FRAP) tests and anti-inflammatory capacity was evaluated by hind paw oedema model using carrageenan-induced inflammation in rat. The acute toxicity was evaluated using mice. RESULTS: Acute toxicity of ethanolic extract of E. arborea showed no sign of toxicity at dose of 5g/kg B.W. Our extracts have important antioxidant properties. The efficient concentration of the ethanolic extract (10.22μg/ml) required for decreasing initial DPPH concentration by 50% was comparable to that of standard solution butyl-hydroxy-toluene (BHT) (8.87μg/ml). The administration of ethanolic extract at doses of 200 and 400mg/kg B.W. was able to prevent plantar oedema and exhibited a significant inhibition against carrageenan-induced inflammation when compared to the control group (NaCl 0.9%) but comparable to those of diclofenac (reference drug). CONCLUSIONS: Our results show that the leaves of E. arborea may contain some bioactive compounds which are responsible for the antioxidant and anti-inflammatory activities observed here. Our finding may indicate the possibility of using the extracts of this plant to prevent the antioxidant and inflammatory processes.
    Pathologie Biologie 12/2013; 61(6):254-258. · 1.67 Impact Factor
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    [Show abstract] [Hide abstract]
    ABSTRACT: Aim The present study was carried out to evaluate the antioxidant and anti-inflammatory capacity, and acute toxicity of Moroccan Erica arborea leaves. Methods Antioxidant capacity was assessed by diphenyle-picryl-hydrazyl (DPPH), phosphomolybdate (PPM) and ferric reducing antioxidant power (FRAP) tests and anti-inflammatory capacity was evaluated by hind paw oedema model using carrageenan-induced inflammation in rat. The acute toxicity was evaluated using mice. Results Acute toxicity of ethanolic extract of E. arborea showed no sign of toxicity at dose of 5 g/kg B.W. Our extracts have important antioxidant properties. The efficient concentration of the ethanolic extract (10.22 μg/ml) required for decreasing initial DPPH concentration by 50% was comparable to that of standard solution butyl-hydroxy-toluene (BHT) (8.87 μg/ml). The administration of ethanolic extract at doses of 200 and 400 mg/kg B.W. was able to prevent plantar oedema and exhibited a significant inhibition against carrageenan-induced inflammation when compared to the control group (NaCl 0.9%) but comparable to those of diclofenac (reference drug). Conclusions Our results show that the leaves of E. arborea may contain some bioactive compounds which are responsible for the antioxidant and anti-inflammatory activities observed here. Our finding may indicate the possibility of using the extracts of this plant to prevent the antioxidant and inflammatory processes.
    Pathologie Biologie 01/2013; 61(6):254–258. · 1.67 Impact Factor

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