MRI Findings of Giant Cell Tumors of the Spine
Sungkyunkwan University, Sŏul, Seoul, South KoreaAmerican Journal of Roentgenology (Impact Factor: 2.73). 08/2007; 189(1):246-50. DOI: 10.2214/AJR.06.1472
OBJECTIVE: The purpose of this article is to describe the MRI features of giant cell tumors of the spine in 10 patients. CONCLUSION: One of the tumors was located in C7. The other nine tumors were located in the thoracic spine, lumbar spine, and sacrum, three in each site. The characteristic findings included an expansile mass with heterogeneous low to intermediate signal intensity on the T2-weighted images (10/10), a curvilinear area of signal void on T1- and T2-weighted images (9/10), and cystic changes within the mass (4/10). Although no imaging feature was pathognomonic, MRI was found to be valuable in identifying the tumor, revealing its extent, and defining its relationship with the intraspinal structures.
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ABSTRACT: ObjectiveTo evaluate the MR imaging features of solitary plasmacytomas of the spine. MethodsThe MR images of 7 patients with histologically proven solitary plasmacytomas of the spine were reviewed. ResultsAll tumors showed predominantly iso- to hypointensity relative to muscle on T1-weighted MR images and intermediate signal intensity between muscle and fat on T2-weighted images. Curvilinear low signal intensity structures were seen within the lesions on T1 and T2-weighted images in five tumors. Moderate to strong enhancement was seen in all 6 tumors that underwent contrast enhanced MR examination. All tumors showed areas of high signal intensity on T2-weighted images and heterogeneous enhancement, except the 2 largest tumors without pathologic fracture in the sacrum. Intervertebral discs were preserved in all tumors. ConclusionThe MR imaging features that suggest plasmacytoma of the spine include predominant intermediate signal intensity on T2-weighted images, curvilinear low signal intensity structures, moderate to strong enhancement, relatively homogeneous appearance if there are no pathologic fracture and preservation of the intervertebral discs.Clinical Oncology and Cancer Research 08/2009; 6(4):241-244. DOI:10.1007/s11805-009-0241-5
Article: Giant Cell Tumor of the Spine[Show abstract] [Hide abstract]
ABSTRACT: Six patients with giant cell tumor of the spine had surgery between 1981 and 1995. Three lesions were located in the scrum, two lesions were in the thoracic spine, and one lesion was in the lumbar spine. Preoperatively, all patients had local pain and neurologic symptoms. Two patients had cement implanted after curettage or intralesional excision of the sacral tumor; one patient had a local relapse. After the second curettage and cement implantation, the tumor was controlled. One patient with a sacral lesion had marginal excision and spondylodesis; no relapse developed. Two patients with thoracic lesions had planned marginal excision and spondylodesis; the margins finally became intralesional, but no relapse developed. One patient with a lumbar lesion had incomplete removal of the tumor and received postoperative irradiation. At the final followup (median, 69 months), five of six patients were disease-free and one patient died of disease progression. Two of the five surviving patients had pain after standing or neurologic problems. Although some contamination occurred, planning a marginal excision of the lesion seems beneficial for vertebral lesions above the sacrum. Total sacrectomy of a sacral lesion seems to be too invasive when cement implantation can control the lesion.Clinical Orthopaedics and Related Research 09/2002; 401(401):194-201. DOI:10.1097/00003086-200208000-00022 · 2.77 Impact Factor
- Value in Health 11/2007; 10(6). DOI:10.1016/S1098-3015(10)65266-7 · 3.28 Impact Factor
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