Using Mismatch Negativity to Study Central Auditory Processing in Developmental Language and Literacy Impairments: Where Are We, and Where Should We Be Going?

Department of Experimental PsychologyUniveristy of Oxford, Oxford, United Kingdom.
Psychological Bulletin (Impact Factor: 14.76). 08/2007; 133(4):651-72. DOI: 10.1037/0033-2909.133.4.651
Source: PubMed


A popular theoretical account of developmental language and literacy disorders implicates poor auditory temporal processing in their etiology, but evidence from studies using behavioral measures has yielded inconsistent results. The mismatch negativity (MMN) component of the auditory event-related potential has been recommended as an alternative, relatively objective, measure of the brain's ability to discriminate sounds that is suitable for children with limited attention or motivation. A literature search revealed 26 studies of the MMN in individuals with dyslexia or specific language impairment and 4 studies of infants or children at familial risk of these disorders. Findings were highly inconsistent. Overall, attenuation of the MMN and atypical lateralization in the clinical group were most likely to be found in studies using rapidly presented stimuli, including nonverbal sounds. The MMN literature offers tentative support for the hypothesis that auditory temporal processing is impaired in language and literacy disorders, but the field is plagued by methodological inconsistencies, low reliability of measures, and low statistical power. The article concludes with recommendations for improving this state of affairs.

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Available from: Dorothy Vera Margaret Bishop, Oct 03, 2015
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    • ", 2011 ) . Deviance detection for speech sounds works similarly to other types of sounds with phonetic features showing categorical effects with respect to the languages spoken by the listener ( for reviews see , Bishop , 2007 ; Näätänen , 2001 ; Pulvermüller & Shtyrov , 2006 ; Rimmele , Sussman , & Poeppel , 2015 ) . Speaker and speech segrega - tion from noise and from other speakers has been extensively stud - ied in the literature ( e . "
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    ABSTRACT: Communication by sounds requires that the communication channels (i.e. speech/speakers and other sound sources) had been established. This allows to separate concurrently active sound sources, to track their identity, to assess the type of message arriving from them, and to decide whether and when to react (e.g., reply to the message). We propose that these functions rely on a common generative model of the auditory environment. This model predicts upcoming sounds on the basis of representations describing temporal/sequential regularities. Predictions help to identify the continuation of the previously discovered sound sources to detect the emergence of new sources as well as changes in the behavior of the known ones. It produces auditory event representations which provide a full sensory description of the sounds, including their relation to the auditory context and the current goals of the organism. Event representations can be consciously perceived and serve as objects in various cognitive operations. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.
    Brain and Language 07/2015; 148:1-22. DOI:10.1016/j.bandl.2015.05.003 · 3.22 Impact Factor
    • "Yet, five studies reported different effects of ISI/ITIs on MMN amplitude and MMN latency, and three of them even exhibited a correlation of ISI/ITI prolongation with MMN peak latency rather than with MMN amplitude. Latency measures are often regarded as being problematic, especially when no sharp peak can be defined (Bishop, 2007; Luck, 2005). However, longer MMN peak latencies may indicate an elongated comparison process between standard and deviant stimuli (Horton, Millar, Labelle, & Knott, 2011), which may be due to the longer intervals preceding the discrimination process. "
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    Psychophysiology 06/2015; 52(9). DOI:10.1111/psyp.12459 · 2.99 Impact Factor
    • "Even if the nature and origin of dyslexia still remain unclear, dyslexics often show phonological deficits (for reviews see, Goswami, 2011; Hämälainen et al, 2013). Although there is still a debate as to whether this phonological deficit is causally linked to a more general deficit in acoustic processing, there is some agreement that the acoustic content of speech, especially its temporal features, are processed abnormally by dyslexic children (Bishop, 2007; Goswami, 2011). To further test this hypothesis, Chobert et al (2012b) conducted a cross-sectional experiment with dyslexic children and normal-readers who passively listened to a sequence of syllables that were close or far from the standard syllable " Ba " and that varied in duration, VOT and frequency. "
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    Neuropsycholinguistic Perspectives on Language Cognition: Essays in Honour of Jean-Luc Nespoulous, Edited by Corinne Astésano, Mélanie Jucla, 06/2015: chapter 7 Influence of musical expertise on the perception of pitch, duration and intensity variations in speech and harmonic sounds: pages 88; Psychology Press.
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