Riedel's Thyroiditis in a Patient with Recurrent Subacute Thyroiditis: A Case Report and Review of the Literature

Department of Internal Medicine, Yonsei University, Sŏul, Seoul, South Korea
Endocrine Journal (Impact Factor: 2). 09/2007; 54(4):559-62. DOI: 10.1507/endocrj.K06-186
Source: PubMed


Riedel's thyroiditis is a rare form of chronic thyroiditis, characterised by a fibroinflammatory process that partially destroys the thyroid and often involves surrounding tissues. The relationship of Riedel's thyroiditis to other forms of thyroiditis is not clear. A case of Riedel's thyroiditis in a 51-year-old woman presenting with symptoms of subacute thyroiditis, is reported. She was diagnosed with subacute thyroiditis based on clinical manifestation and laboratory results. She was treated with glucocorticoids for six weeks, and then followed-up for 12 months. Three years later, she visited with tenderness and enlargement of thyroid mass, and laboratory and radiology findings suggested that she had a malignant thyroid tumor as well as subacute thyroiditis. After thyroidectomy, histopathologic findings showed that she had Riedel's thyroiditis in the presence of subacute thyroiditis. Until now, few cases of Riedel's thyroiditis in patients with a history of subacute thyroiditis have been reported in the literature. Although the etiology of Riedel's thyroiditis is unknown, it may develop in the course of subacute thyroiditis.

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    • "Two women, first diagnosed with sub-acute thyroiditis, developed an enlargement of the thyroid gland and symptoms of compression eight months and three years later, respectively. Post-operative histopathologic evaluation showed Riedel's thyroiditis characteristics associated with sub-acute thyroiditis [127,128]. "
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    ABSTRACT: Viral infections are frequently cited as a major environmental factor involved in subacute thyroiditis and autoimmune thyroid diseases This review examines the data related to the role of viruses in the development of thyroiditis. Our research has been focused on human data. We have reviewed virological data for each type of thyroiditis at different levels of evidence; epidemiological data, serological data or research on circulating viruses, direct evidence of thyroid tissue infection. Interpretation of epidemiological and serological data must be cautious as they don't prove that this pathogen is responsible for the disease. However, direct evidence of the presence of viruses or their components in the organ are available for retroviruses (HFV) and mumps in subacute thyroiditis, for retroviruses (HTLV-1, HFV, HIV and SV40) in Graves's disease and for HTLV-1, enterovirus, rubella, mumps virus, HSV, EBV and parvovirus in Hashimoto's thyroiditis. However, it remains to determine whether they are responsible for thyroid diseases or whether they are just innocent bystanders. Further studies are needed to clarify the relationship between viruses and thyroid diseases, in order to develop new strategies for prevention and/or treatment.
    Virology Journal 02/2009; 6(1):5. DOI:10.1186/1743-422X-6-5 · 2.18 Impact Factor
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    ABSTRACT: Riedel's thyroiditis (RT) is a rare form of infiltrative and inflammatory disease of the thyroid, first described by Bernard Riedel in 1896. The concurrent presence of RT and other thyroid diseases has been reported, but, the association of RT with Hashimoto's thyroiditis and acute thyroiditis has not yet been reported. We present a case of concurrent Riedel's, Hashimoto's and acute thyroiditis that occurred in a 45-year-old patient.
    Case Reports in Medicine 02/2009; 2009:535974. DOI:10.1155/2009/535974
  • Cytopathology 04/2010; 21(2):123-6. DOI:10.1111/j.1365-2303.2009.00705.x · 1.48 Impact Factor
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