Symptomatic bladder endocervicosis: Does it need surgery? - A case report and review of the literature
Department of Urology, Wrexham Maelor Hospital, Wrexham, UK. Urologia Internationalis
(Impact Factor: 1.43).
02/2007; 79(1):86-9. DOI: 10.1159/000102921
Endocervicosis of the urinary bladder is a rare benign condition exclusively seen in women, usually of reproductive age. To the best of our knowledge there are only about twenty cases reported so far. It causes non-specific symptoms and is seen as a submucosal lesion on cystoscopy. On histological examination one finds endocervical glands embedded deep within the muscle layers. It can be confused with an adenocarcinoma of the bladder. Unless the correct diagnosis is made these patients can undergo potentially debilitating surgery. As demonstrated in our patient even symptomatic endocervicosis can be managed conservatively.
Available from: Alberto Guffanti
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ABSTRACT: In this talk we describe our approach for the computation of multi-leg one-loop amplitudes and present some first results relevant for LHC phenomenology.
Nuclear Physics B - Proceedings Supplements 10/2006; 160(160):61-65. DOI:10.1016/j.nuclphysbps.2006.09.102 · 0.88 Impact Factor
Acta cytologica 01/2010; 54(5 Suppl):1061-3. · 1.56 Impact Factor
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ABSTRACT: Endocervicosis of the urinary bladder is a very rare tumor-like benign lesion. In the present report, a case in a 34-year-old woman, who has a prior Caesarean section at the age of 30 and 2-years history of dysuria, is described. Transvaginal ultrasound, cystoscopy and magnetic resonance imaging demonstrated a solid mass in the posterior wall of the bladder. The mass was removed and histology revealed a haphazard proliferation of endocervical-type mucinous glands scattered through the muscularis propria of bladder wall. Immunohistochemical phenotype of these glands was compared with three normal uterine endocervices and two cases of well-differentiated mucinous adenocarcinoma of the uterine cervix. Endocervicosis glands displayed positive reaction for antibodies against estrogen receptor, progesterone receptor, CAM 5.2, cytokeratin 7, CA125, HBME-1 and carcinoembryonic antigen, which showed positivity in normal endocervices. On the other hand, only glands of well-differentiated mucinous adenocarcinoma expressed human gastric mucin and showed high proliferative index of Ki-67. These results supported the hypothesis of its Müllerian origin. Furthermore, diffuse distribution of estrogen and progesterone receptors, lack of human gastric mucin and low proliferative activity were distinct features for endocervicosis compared to well-differentiated mucinous adenocarcinoma.
Pathology International 07/2010; 60(7):528-32. DOI:10.1111/j.1440-1827.2010.02555.x · 1.69 Impact Factor
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