Article

Seroepidemiology of infection with Toxoplasma gondii in healthy blood donors of Durango, Mexico

Faculty of Medicine, Juárez University of Durango State (UJED), Durango, Mexico.
BMC Infectious Diseases (Impact Factor: 2.61). 02/2007; 7:75. DOI: 10.1186/1471-2334-7-75
Source: PubMed

ABSTRACT Toxoplasma gondii (T. gondii) infection in blood donors could represent a risk for transmission in blood recipients. There is scarce information about the epidemiology of T. gondii infection in blood donors in Mexico. Therefore, we sought to determine the prevalence of T. gondii infection and associated socio-demographic and behavioral characteristics in a population of healthy blood donors of Durango City, Mexico.
Four hundred and thirty two blood donors in two public blood banks of Durango City, Mexico were examined for T. gondii infection between August to September 2006. Blood donors were tested for anti-T. gondii IgG and IgM antibodies by using enzyme-linked immunoassays (Diagnostic Automation Inc., Calabasas, CA, USA). Socio-demographic and behavioral characteristics from each participant were also obtained.
Thirty two (7.4%) of 432 blood donors had IgG anti-T. gondii antibodies. Eight (1.9%) of them had also IgM anti-T. gondii antibodies. Multivariate analysis using logic regression showed that T. gondii infection was associated with the presence of cats at home (adjusted OR = 3.81; 95% CI: 1.45-10.01). The age group of 45-60 years showed a significantly higher frequency of T. gondii infection than the group of 25-34 years (p = 0.02). Blood donors without education had a significantly higher frequency of infection (15.8%) than those with 13-19 years of education (4.5%) (p = 0.04). Other characteristics of blood donors including male gender, consumption of undercooked meat or blood transfusion did not show an association with infection.
The prevalence of T. gondii infection in healthy blood donors of Durango City, Mexico is lower than those reported in blood donors of south and central Mexico, and is one of the lowest reported in blood donors worldwide. T. gondii infection in our blood donors was most likely acquired by contact with cats. Prevalence of infection increased with age and decreased with educational level.

Download full-text

Full-text

Available from: Oliver Liesenfeld, Jul 29, 2015
0 Followers
 · 
294 Views
  • Source
    • "2005). Transmission may occur by eating uncooked or undercooked meat, contaminated vegetables, by blood transfusion, organ transplantation and across the plancenta from the mother to the foetus (Bisson et al., 2000; Dubey, 2004; Alvarado-Eguivel et al., 2007). Toxoplasmic encephalitis (TE) occurs almost exclusively because of reactivation of latent tissue cysts (Luft et al., 1984; Israelisk et al., 1993). "
  • [Show abstract] [Hide abstract]
    ABSTRACT: This paper reports on work being undertaken to enhance the performance and safety of road sweeping vehicles, including a forward looking debris detection system alongside research into brushes and the brushing process. Vision processing techniques are used to identify various road surfaces and debris. A continuous flow of data is provided by laser striping building up a 3D profile of the road ahead. Only when the scene cannot be fully identified with sizes and shapes alone, other more advanced image processing techniques are applied. A brush rig was constructed to test different brush types used on road sweeping vehicles. An extensive range of practical tests were undertaken on a variety of contact surfaces. Analysis of the results shows that the common brush types currently on the market have very different characteristics depending on the orientation of their tines
    Advanced Intelligent Mechatronics, 2001. Proceedings. 2001 IEEE/ASME International Conference on; 02/2001
  • Source
    [Show abstract] [Hide abstract]
    ABSTRACT: There is scarce information concerning the epidemiology of Toxoplasma gondii infection in people of rural Mexico. Anti-T. gondii immunoglobulin (Ig)G and IgM antibodies were sought in 462 adult inhabitants from 3 rural communities of Durango, Mexico, using enzyme-linked immunoassays. In total, 110 (23.8%) of 463 persons had IgG anti-T. gondii antibodies. Ten (2.2%) of them also had IgM anti-T. gondii antibodies. Prevalences of T. gondii IgG antibodies in the 3 communities varied from 14.8 to 35.8%. The highest prevalence of infection was observed in participants older than 70 yr and in those with good housing conditions. Toxoplasma gondii infection was significantly associated with consumption of squirrel (adjusted odds ratio [OR] = 4.22; 95% confidence interval [CI] = 1.11-16.05) and turkey meat (adjusted OR = 4.58; 95% CI = 1.14-18.44). This is the first epidemiological study of T. gondii prevalence in rural Mexico.
    Journal of Parasitology 04/2008; 94(4):811-6. DOI:10.1645/GE-1524.1 · 1.26 Impact Factor
Show more