FNA diagnosis of retroperitoneal leiomyosarcoma metastasizing to the breast

Department of Pathology, Loyola University Medical Center, Maywood, Illinois, USA.
Diagnostic Cytopathology (Impact Factor: 1.12). 08/2007; 35(8):508-11. DOI: 10.1002/dc.20664
Source: PubMed


Fine-needle aspiration (FNA) biopsy is one of the first-line investigations in any breast lump, and hence cytomorphological recognition of nonmammary metastatic tumors to the breast and their distinction from primary tumors is important. Breast metastasis from extra-mammary malignancy is rare, constituting 2% of breast tumors; even rarer are metastatic leiomyosarcomas. Our patient presented with a breast lump 2 years after operative removal of a retroperitoneal leiomyosarcoma. The breast lump was confirmed to be a metastasis from the earlier primary. Herein, we report the first case of a retroperitoneal leiomyosarcoma metastatic to the breast diagnosed by Fine Needle Aspiration.

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