Relationship of body mass index with asthma indicators in Head Start children

Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock 72202-3591, USA.
Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology (Impact Factor: 2.6). 08/2007; 99(1):22-8. DOI: 10.1016/S1081-1206(10)60616-3
Source: PubMed

ABSTRACT To examine the relationship of body mass index (BMI) and asthma indicators on children with asthma in a Head Start (HS) program.
In this cross-sectional study (November 18, 2000, to December 12, 2003) of children aged 3 to 5 years with asthma, we compared the BMI data of HS asthmatic patients (n = 213) with the data of peer control subjects from a sample (n = 816) of the National Health and Nutrition Examination Survey aged 3 to 5 years and with children in prekindergarten in Arkansas public schools (n = 1,024). Parental reports of asthma symptoms, health care use, medication use, school days missed, and quality of life were used as indicators of asthma morbidity. Categorical analysis and chi2 tests were performed to examine the relationship between BMI and asthma morbidity.
The prevalence of overweight (> or =95th percentile) was significantly higher in HS children with asthma compared with the National Health and Nutrition Examination Survey children (P < .001) and Arkansas prekindergarten children (P = .05). Compared with HS asthmatic children with a BMI less than the 85th percentile, HS asthmatic patients with a BMI of the 85th percentile or greater reported significantly more school days missed (P = .02), lifetime hospitalizations (P = .04), emergency department visits (P = .02), and activity limitations (P = .03) and fewer oral corticosteroid bursts (P = .04). There was also a trend for more daytime symptoms (P = .05) and lower quality of life (P = .06). No differences were observed in rescue (P = .28) or controller (P = .47) medications, environmental tobacco smoke exposure (P = .47), positive allergy test results (P = .85), and nighttime symptoms (P > .99).
Having an increased BMI was associated with more asthma morbidity in this group of HS asthmatic patients. Despite the lack of a clear explanation for the link between asthma and BMI, our data suggest that an increased BMI significantly affects the well-being of young asthmatic patients and should be further addressed.

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    • "AHR) (Bibi et al. 2004) or serum lipid profile and IgE level (Leung et al. 2009). In addition, some studies gathered indicators representing asthma severity such as emergency room visits; school days missed, or rescue medication usage to capture a more thorough picture of the children's asthma severity (Belamarich et al. 2000, Bibi et al. 2004, Vargas et al. 2007, Jacobson et al. 2008). Though there was heterogeneity regarding the definition of childhood obesity across reviewed studies, half of them agreed that the 85th and 95th BMI percentiles were applicable cut-off points to identify overweight/obese children. "
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    Journal of Advanced Nursing 04/2013; 69(7). DOI:10.1111/jan.12129 · 1.74 Impact Factor
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    • "Additionally, regulatory genes for ORMDL3 [8] and IL12B [9] have been associated with asthma severity. Environmental exposures have also been associated with asthma severity and include tobacco smoke[10] and outdoor air pollution[11]; there is also evidence of increased asthma severity in association with obesity[12] and reduced dietary antioxidants[13]. Whilst gene-environment interactions are described for asthma causation in children [14,15] there is also the potential for such interactions to explain why asthma severity varies within a population[16]. "
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    BMC Medical Research Methodology 12/2010; 10(1):107. DOI:10.1186/1471-2288-10-107 · 2.27 Impact Factor
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    • "Escore Z: (altura/idade; peso/idade) IMC Não houve comprometimento da altura e do peso corporal nas crianças e adolescentes que usaram corticoesteróídes inalatórios mais de 1 ano e em doses recomendadas para o tratamento da asma. Carroll et al.,2006 16 n=209 crianças admitidas na UTI com asma Peso corporal Peso normal (<95% do peso para idade percentil) Obeso (> 95% do peso para idade) 45 (22%) eram obesos Brockmann et al.,2007 17 n=40 crianças asmáticas n=41 controlos IMC Questionário para actividade física 15 crianças asmáticas obesas/sobrepeso; 11 crianças controlos obesas/sobrepeso; As asmáticas realizam menos actividade física comparadas com as controlos Vargas et al., 2007 18 n=213 crianças asmáticas n=816 controlos. 03 a 05 anos IMC A prevalenca de baixo peso (percentil ≥ 95) foi mais signifi cativa nas crianças com asma "
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