Article

Cementless hip arthroplasty in Paget's disease at medium-term follow-up (average of 6.7 years).

Sydney Hip & Knee Surgeons, Sydney, NSW, Australia; Australian Institute of Musculo-Skeletal Research, St Leonards, NSW, Australia.
The Journal of Arthroplasty (impact factor: 2.38). 09/2007; 22(5):692-6. DOI:10.1016/j.arth.2006.09.010 pp.692-6
Source: PubMed

ABSTRACT We performed 33 cementless total hip arthroplasties for arthritis in 27 patients with an established diagnosis of Paget's disease on the acetabular or femoral side of the hip. There were 3 revisions. One stem for aseptic loosening at 55 months, and 2 stems after periprosthetic fractures at 9 and 70 months. Twenty-three cases were available for follow-up at an average of 6.7 years (range, 2-14 years). Harris hip score improved from 56/100 preoperatively (16-98/100) to 90/100 postoperatively (78-100/100). All surviving components were radiographically bone ingrown. Based on our findings, it appears that a cementless total hip arthroplasty can have a good outcome in Paget's disease.

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  • Article: The Second Most Common Bone Disease: A Review on Paget’s Disease of Bone
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    ABSTRACT: Paget disease of bone (PDB) is the second most common metabolic bone disease. It is a chronic disease with a mono- or polyostotic appearance that is characterized by an increased bone turnover. The orthopedic surgeon is often confronted with such symptoms and complications as bone pain, skeletal deformities, and pathologic fractures caused by the “out-of-balance bone remodeling process”. Careful evaluation of the clinical and radiographic findings is necessary to determine whether treatment of PDB is indicated. The mode of action of effective pharmacological treatments consists of reducing the increase in osteoclast-mediated bone resorption that characterizes the disease. Bisphosphonates are the compounds of choice for PDB therapy; these are readily available and have received approval. Patients with PDB are at increased risk for surgical complications, such as blood loss and heterotopic bone formation, if operative treatment is necessary. However, advances in surgical techniques and accompanying medical treatment could potentially improve the overall outcome of these patients. To achieve that goal, careful perioperative interdisciplinary management and monitoring are essential.
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Keywords

33 cementless total hip arthroplasties
 
70 months
 
arthritis
 
cementless total hip arthroplasty
 
follow-up
 
good outcome
 
Harris hip score
 
Paget's disease
 
periprosthetic fractures
 

Patrick James Lusty