Article

Nutrition as a determinant of successful aging: description of the Quebec longitudinal study Nuage and results from cross-sectional pilot studies.

Laboratory of Neuroendocrinology of Aging, Centre hospitalier de l'Université de Montréal Research Center and Department of Medicine, Institut Universitaire de Gériatrie de Montréal, Canada.
Rejuvenation Research (impact factor: 3.83). 10/2007; 10(3):377-86. DOI:10.1089/rej.2007.0596 pp.377-86
Source: PubMed

ABSTRACT Optimal nutrition is essential for general well being, maintenance of physical and functional capacities and prevention of chronic disease in the elderly. The 5-year longitudinal study, NuAge, was designed to assess the pivotal role of nutrition on physical and cognitive status, functional autonomy and social functioning. A cohort of 1793 men and women, selected from three age groups (68-72, 73-77, 78-82) at recruitment, has been followed annually since 2003-2004. A plurimethodological approach, including basic, clinical, epidemiologic, and social research has been used. Data on various facets of nutritional status (diet, food habits, appetite, anthropometry and body composition), and functional (muscle strength, physical activity, physical and functional capacities and performance), medical (physical, mental and cognitive health, medication) and social data (network, support, participation) are collected by questionnaires or direct measurements. Blood, urine, and saliva samples are also collected and processed for genomic, transcriptomic, proteomic, and biochemical analyses and to study markers of endocrine, immune, and cognitive functions. Selected bio-psycho-social characteristics of the cohort, consumption of macronutrients, and biologic variables are presented, including the impact of intake of certain foods on total antioxidant status. Understanding the aging process as regulated by a modifiable factor such as nutrition should facilitate the development of targeted strategies for promoting successful aging.

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    BMC Geriatrics 01/2008; 8:20. · 2.34 Impact Factor
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Keywords

5-year longitudinal study
 
age groups
 
aging process
 
bio-psycho-social characteristics
 
biochemical analyses
 
biologic variables
 
body composition
 
chronic disease
 
functional autonomy
 
muscle strength
 
nutritional status
 
Optimal nutrition
 
physical activity
 
pivotal role
 
plurimethodological approach
 
social data
 
social research
 
study markers
 
total antioxidant status
 
various facets