Retrospective analysis of seizures associated with feline infectious peritonitis in cats.
ABSTRACT Seizures have been reported frequently in feline infectious peritonitis (FIP) but have not been studied in detail in association with this disease. The purpose of this study was to perform a retrospective analysis of neurological signs in a population of 55 cats with a histopathologically confirmed neurological form of FIP. Seizure patterns were determined and it was attempted to relate occurrence of seizures with age, breed, sex and neuropathological features. Fourteen cats had seizure(s), while 41 cats had no history of seizure(s). Generalised tonic-clonic seizures were seen in nine cats; and complex focal seizures were observed in four patients. The exact type of seizure could not be determined in one cat. Status epilepticus was observed in one patient but seizure clusters were not encountered. Occurrence of seizures was not related to age, sex, breed or intensity of the inflammation in the central nervous system. However, seizures were significantly more frequent in animals with marked extension of the inflammatory lesions to the forebrain (P=0.038). Thus, the occurrence of seizures in FIP indicates extensive brain damage and can, therefore, be considered to be an unfavourable prognostic sign.
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ABSTRACT: Despite its theoretical and managerial significance, subsidiary entrepreneurship and its effects on subsidiary contribution remain underexplored in the literature. We propose that subsidiary entrepreneurship encourages more creative strategic responses to escalating environmental change. We explore the direct and mediating effects of subsidiary entrepreneurship on subsidiary contribution to the MNC, particularly subsidiary strategy creativity. We use structural equation modelling to test our propositions on data generated from surveying the population of Irish subsidiaries of foreign MNCs, and find strong support for our theoretical predictions. The managerial implications of subsidiary entrepreneurship in generating creative strategy, prompting strategic initiatives and improving performance are discussed.Journal of International Management 12/2010; 16(4):328-339. · 1.70 Impact Factor
Article: Cerebral toxoplasmosis in a cat[Show abstract] [Hide abstract]
ABSTRACT: A five year-old semi-stray intact tom cat with acute multifocal neurological signs, including seizures, opisthotonus and horizontal nystagmus was presented to the veterinary clinic. The onset of severe neurological signs was sudden but preceded by a mild left-hand head tilt, which had been observed for the previous two weeks. Results of in-house tests for both FeLV antigen and FIV antibody were negative although the owner claimed that the cat had been diagnosed as seropositive to FIV infection in the first year of life. Despite antibacterial and symptomatic treatment the state of the cat tended to deteriorate and eventually euthanasia was performed. The examination of the cerebrospinal fluid (CSF) using polymerase chain reaction (PCR) revealed the presence of T. gondii DNA. No bacteria, fungi or feline coronavirus RNA were detected in the microbiological and molecular examination of CSF. Thus, cerebral toxoplasmosis was recognized.Medycyna weterynaryjna 11/2010; 66(11):784-786. · 0.20 Impact Factor
Article: Seizures and epilepsy in cats[Show abstract] [Hide abstract]
ABSTRACT: Seizures are a common presenting complaint in cats, although causes and options for treatment of seizures in this species have been historically poorly described in the veterinary literature. Seizure manifestation in cats may be different than what is typically seen in dogs, but underlying causes of seizure activity are the same. These include primary epilepsies, structural epilepsies, and reactive seizures. While primary epilepsy was once believed to be rare in cats, we now commonly appreciate this syndrome, albeit at a lower frequency than in dogs. Because of this, a complete diagnostic work up is recommended for all cats presenting for initial evaluation of seizures. Symptomatic treatment of seizures in cats is similar to dogs, with only a few limitations related to species-specific anti-epileptic drug toxicities. The goal of this review is to summarize the recent veterinary literature related to feline seizures with a focus on seizure classification, clinical manifestation, diagnostic evaluation, and treatment options.Veterinary Medicine: Research and Reports. 07/2014; 5.