State of the Art: Non-Invasive Ultrasound Assessment of the Uteroplacental Circulation

Department of Obstetrics and Gynecology, University of Milan Bicocca, San Gerardo Hospital, Monza, Italy.
Seminars in Perinatology (Impact Factor: 2.68). 09/2007; 31(4):232-9. DOI: 10.1053/j.semperi.2007.06.002
Source: PubMed


Impaired trophoblastic invasion of the maternal spiral arteries is associated with increased risk for subsequent development of intrauterine growth restriction, preeclampsia, and placental abruption. A series of screening studies involving assessment of impedance to flow in the uterine arteries have examined the potential value of Doppler in identifying pregnancies at risk of the complications of impaired placentation. Currently we are able to characterize uteroplacental perfusion with quantitative and qualitative methodologies. This review will examine both methodologies and seek to highlight conclusive and inconclusive findings.

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    • "Doppler ultrasound enables the assessment of blood flow parameters for the adequate and reduced perfusion in vivo. Impaired trophoblastic invasion of the maternal spiral arteries is shown to be associated with increased impedance to flow in the waveforms obtained by Doppler ultrasound examination of the UtA [20] [21]. Bilateral high-resistance flow velocity waveforms with early diastolic notches at 22nd–26th gw are associated with subsequent fetal death, intrauterine growth restriction (IUGR) and preeclampsia [22]. "
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