Simple anthropometric indices in relation to cardiovascular risk factors in Chinese type 2 diabetic patients.

Department of Endocrinology, Union Hospital, Tongji Medical School, Huazhong Technology University, Wuhan 430022, Hubei, PR China.
The Chinese journal of physiology (Impact Factor: 0.75). 06/2007; 50(3):135-42.
Source: PubMed

ABSTRACT To determine which is the best anthropometric index among body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) and waist to height ratio (WHtR) in type 2 diabetic patients, we examined the relationship between these indices and cardiovascular risk factors using partial correlation analysis, chi-square test, logistic regression analysis and Receiver Operator Characteristic (ROC) curves. Partial correlation analysis showed that among the 4 obesity indices, WHtR had the highest r values for all the cardiovascular risk factors in both sexes, followed by WC. Chi-square analysis which revealed that an increased WHtR was more strongly associated with hypertension, hypertriglyceridemia (high TG) and low high-density lipoprotein cholesterol (HDL-C) than the other indices. Logistic regression analysis showed that, after controlling for age, the hypertension, high TG and low HDL-C odds ratios of WHtR > or = 0.5 were 2.56 (95% CI: 1.24, 5.29), 2.87 (95% CI: 1.43, 5.78), 2.59 (95% CI: 1.03, 6.59) in men and 3.75 (95% CI: 1.75, 8.05), 3.21 (95% CI: 1.52, 6.79), 3.62 (95% CI: 1.43, 9.21) in women, respectively. In ROC analysis, the areas under curve of WHtR were the largest for at least one risk factor in both men and women. These results indicated that WHtR had a higher correlation with cardiovascular risk factors than WC, WHR or BMI in newly diagnosed type 2 diabetes. We proposed the measurement of WHtR as a screening tool for cardiovascular risk factors in this population.

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    Public Health Theses. Paper. 01/2008; 42.
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    ABSTRACT: To determine whether waist-to-height ratio correlates with coronary artery disease (CAD) severity better, than the body mass index (BMI) as assessed by coronary angiography in Bangladeshi population. This cross sectional study was done on patients in Department of Cardiology in DMCH and those referred in the cath-lab of the Department of Cardiology for CAG during November 2009 to October 2010 involving 120 patients. They were divided into group-A (with coronary score >=7) and group-B (coronary score <7) depending on Gensisni score.Result: There were no statistically significant difference regarding the distribution of age, sex and clinical diagnosis and parameters between the two groups. The mean age of patients was 51.7 +/- 8.2 years and 48.8 +/- 9.1 years in Group A and Group B respectively with a male predominance in both the groups. Patients in group A had higher BMI >=25 and waist to height ratio (>=0.55) than Group B which showed a statistically significant association (p < 0.001). Though a significant positive correlation (r = 0.296, p = 0.006) was observed between BMI and Coronary artery disease score in group A patients, scenario was reverse fro group B (r = 0.076, p = 0.659). The statement was also true for Waist-to-height ratio and Waist-to-height ratio with BMI. Multivariate analysis also yeilded that a patient with BMI >=25 kg/m2 and waist-to height ratio of >=0.55 are 3.06 times and 6.77 times, more likely to develop significant coronary artery disease respectively. The waist-to-height ratio showed better correlation with the severity of coronary artery disease than the BMI.
    BMC Research Notes 04/2014; 7(1):246.
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    ABSTRACT: Diet and anthropometic measures are important indicators of risk of various complications in type 2 diabetics. The purpose was to assess the hypothesis that there would be gender differences in anthropometric measures and dietary intakes for energy and energy-yielding nutrients including oleic acid in the study population of well-controlled (HbA1c < 8 %) Caucasian type 2 diabetics. Males (n=18) and females (n = 14) participated. Subjects came in for two visits each 3 months apart. Males differed from females only in height (m) (1.72 + 0.02 vs 1.59 ± 0.01), hip circumference (cm) (103.0 ± 1.4 vs 117.8 ± 3.9), waist to hip ratio (0.99 ± 0.01 vs 0.87 ± 0.01 and waist to height ratio (0.591 ± 0.010 vs 0.640 ± 0.018). Despite a higher intake for total calories in males and similar intakes for the energy yielding nutrients including oleic acid in the study population of type 2 diabetics, males and females had similar weights and waist circumferences while males had greater waist to hip ratios, lesser waist to height ratios and very a strong trend toward lesser BMI. Females are further away from recommended anthropometric targets and as such appear to be at greater risk of complications from type 2 diabetes. Introduction Cape Breton Island and in particular the Cape Breton regional municipality in the province of Nova Scotia, Canada suffers from among the highest rates of obesity 1 and type 2 diabetes in Canada, the consequence of which are seen in the overall economy and in the competition for healthcare dollars with other health issues. Consequently it is important to control this disease as much as possible so as to reduce its economic and social impact. There appear to be no reports that collectively assess gender equity for type 2 diabetes in terms of all the anthropometric measures mentioned in this paper. Such information is of clear importance for the medical, economic and social impacts and management of this disease. Increased waist, waist to height and waist to hip ratios, as well as BMI enhance the risk of complications (glucose intolerance, hypertension, dyslipidaemia, inflammation) associated with type 2 diabetes in men and women.
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