Article

Natural killer T cells: A bridge to tolerance or a pathway to rejection?

University of Oxford, Oxford, England, United Kingdom
Transplantation (Impact Factor: 3.78). 10/2007; 84(6):679-81. DOI: 10.1097/01.tp.0000280551.78156.ac
Source: PubMed

ABSTRACT Over the past 20 years, natural killer T (NKT) cells have been shown to play an important role in both innate and adaptive immune responses. In this review, the potential role of NKT cells in transplantation will be discussed, particularly their role in rejection and the induction of a state of tolerance.

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