Investigation of the rate of meningitis in association with urinary tract infection in infants 90�days of age or younger

Murdoch Children's Research Institute, Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Emergency medicine Australasia: EMA (Impact Factor: 1.22). 11/2007; 19(5):464-9. DOI: 10.1111/j.1742-6723.2007.01001.x
Source: PubMed

ABSTRACT To test the hypothesis that urinary tract infections (UTI) in young infants are rarely associated with meningitis.
We undertook a review of the laboratory results from 322 infants, 90 days of age or younger, with an admission or discharge diagnosis of UTI or meningitis. The study was conducted in a tertiary paediatric hospital. The primary outcome measure was the incidence of coexisting urinary tract and cerebrospinal fluid sepsis.
In total, 161 of the 322 (50%) infants with an admission or discharge diagnosis of UTI or meningitis were subsequently shown to have a culture-proven UTI. Of the children with a culture-proven UTI, 75 (47%) had cerebrospinal fluid obtained. We detected one case of probable bacterial meningitis in association with UTI.
UTI is rarely associated with meningitis in infants 90 days of age or younger.

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