Article

Antibiotic prophylaxis in cardiac surgery--general principles.

Department of Infections Diseases, Orebro University Hospital, Orebro, Sweden.
Apmis (impact factor: 1.99). 10/2007; 115(9):1012-5. DOI:10.1111/j.1600-0463.2007.00834.x pp.1012-5
Source: PubMed

ABSTRACT Appropriate antibiotic prophylaxis in cardiac surgery can substantially reduce the number of postoperative infections. To avoid misuse, special concerns - such as timing and duration of antibiotics - must be taken into account. Increasing evidence supports that 24 h antibiotic prophylaxis is sufficient for most major surgical procedures. The prophylactic antibiotic should cover the spectrum of bacteria that are likely to be encountered. The emergence of MRSA raises special questions of antibiotic choice as well as route of administration.

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Keywords

24 h antibiotic prophylaxis
 
antibiotic choice
 
antibiotics
 
Appropriate antibiotic prophylaxis
 
bacteria
 
cardiac surgery
 
Increasing evidence
 
major surgical procedures
 
MRSA
 
postoperative infections
 
prophylactic antibiotic