Did thirst-blockers like angiotensin-converting-enzyme inhibitors, sartans, serotonine-re-uptake-inhibitors, dopamine agonists/antagonists, or atypical neuroleptics contribute to the exorbitant number of fatalities during the French 2003 heat wave?
Pharmacoepidemiology and Drug Safety (Impact Factor: 3.17). 12/2007; 16(11):1252-3. DOI: 10.1002/pds.1456
Article: Hydration and Medication Use[Show abstract] [Hide abstract]
ABSTRACT: Hydration is an important part of overall health and also appears to be necessary for the prevention of adverse effects associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs). Evidence has shown that this type of medication does little to prevent the onset of muscle soreness and/or damage when used prior to or during physical activity. However, taking this medication while dehydrated may lead to decreased kidney function. Therefore, NSAIDs should be reserved for pain relief and injury treatment. Additionally, an individual’s hydration status can be affected by medications that have the potential to alter thirst sensation, leading to decreased fluid intake, and diuretics, which lead to increased urine output. It is important for individuals taking these medications to be aware of how they may affect hydration status.American Journal of Lifestyle Medicine 07/2011; 5(4):332-335.
- Pharmacoepidemiology and Drug Safety 04/2008; 17(3):312-3. · 2.90 Impact Factor
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