Rhabdomyoma of the Parapharyngeal Space Presenting with Dysphagia
Department of Otolaryngology, Head and Neck Surgery, National Cancer Institute Regina Elena, Via E. Chianesi 53, 00144 Rome, Italy.Dysphagia (Impact Factor: 2.03). 07/2008; 23(2):202-4. DOI: 10.1007/s00455-007-9125-0
Rhabdomyoma is an exceedingly rare soft tissue benign tumor of skeletal muscle origin classified into cardiac and extracardiac types based on location. Extracardiac rhabdomyoma is further classified into adult, genital, and fetal type depending on the degree of differentiation. Adult rhabdomyomas are rare, but morphologically characteristic, benign mesenchymal tumors with mature skeletal muscle differentiation that in 90% of cases arise in the head and neck region, mainly in the mucosa of the oropharynx, nasopharynx, and larynx, from the branchial musculature of third and fourth branchial arches. Most patients are between 40 and 70 years old, with a mean age of 60 years with a male predominance. Usually presenting symptoms include upper airway obstruction, Eustachian tube dysfunction, and mucosal or neck mass, but rarely does it arise as pure dysphagia. This article presents a case of parapharyngeal rhabdomyoma presenting with only progressive dysphagia.
- Journal of Bronchology 01/2008; 15(4):262-263. DOI:10.1097/LBR.0b013e31818550c6
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ABSTRACT: Rhabdomyomas are rare benign mesenchymal tumors with skeletal muscle differentiation. They are less commonly encountered than are their malignant counterparts, rhabdomyosarcomas. Rhabdomyomas fall into 2 general categories: cardiac and extracardiac types. Extracardiac rhabdomyomas are among the rarest tumors in humans and can be subclassified as fetal, juvenile, and adult types depending on the individual tumor's degree of differentiation by light microscopy. Adult extracardiac rhabdomyoma has a strong predilection for occurrence in the head and neck, mainly in the area of larynx and pharynx. In this article, 2 cases of parapharyngeal rhabdomyoma are reported together with a review of the world literature.American journal of otolaryngology 04/2010; 32(3):240-6. DOI:10.1016/j.amjoto.2010.01.007 · 0.98 Impact Factor
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ABSTRACT: Changes that occur as a natural part of senescence in the complex action of deglutition predispose to dysphagia and aspiration. This dysfunction is worsened in patients with preexisting anatomic or functional alteration such as in case of a postsurgical lower cranial nerve palsy. We present the case of a 72-year-old woman who underwent surgical resection of a right jugulotympanic tumor 33 years ago, resulting in lower cranial nerve palsy, and came to our attention referring a 4 months' history of progressive dysphagia in which a pharyngolaryngeal submucosal mass was suspected.The Journal of craniofacial surgery 09/2011; 22(5):1941-4. DOI:10.1097/SCS.0b013e31821151d0 · 0.68 Impact Factor
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