[To analyse diagnosis, management and prognosis of florid cystitis glandularis (pseudoneoplastic entity)].

Service d'urologie CHU Fattouma Bourguiba Monastir, Tunisie.
Progrès en Urologie (Impact Factor: 0.66). 10/2007; 17(5):968-72.
Source: PubMed


To analyse diagnosis, management and prognosis of florid cystitis glandularis (pseudoneplastic entity).
A retrospective study of 6 consecutive patients with florid cystitis glandularis seen at the department of Urology of Monastir (Tunisia) from January 1996 to July 2006. All patients underwent ultrasonography, and cystoscopy. Computed tomography (CT) was performed in four patients and magnetic resonance imaging (MRI) in one patient.
The six patients, all of whom were male, ranged from 22 to 68 (average 42) years of age. The most common complaints was haematuria. Radiological examination and cystoscopy suggested a bladder tumor in all patients. Histopathology revealed features of cystitis glandularis of intestinal type. Features of the pelvic CT and MRI were consistent with the diagnosis of pelvic lipomatosis in one patient. The endoscopic resection was performed in 5 patients. Recurrence occurred in one of these 5 patients within one and 7 years of follow-up. The other patient had developed a low compliance small-capacity bladder and bilateral ureteral obstruction. A total cystoprostatectomy and ileal neobladder construction was considered, but it was declined by the patient. The patient was treated with anti-inflammatory drug (Indometacine 100 mg/day).
Cystitis glandularis may be mistaken for bladder tumor The diagnosis is histological. Treatment is based on eradication of the irritative factors and endoscopic resection of the tumoral masses. The clinical course is unclear, requiring long-term fellow-up.

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    • "The extensive form of CG can also cause compression of the intramural ureteral segments with dilation of the upper urinary tract and development of ureterohydronephrosis and chronic renal failure. Such cases often present symptoms associated with pyelonephritis resulting from a primary or secondary infection of the urinary system [5]. "
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    ABSTRACT: Cystitis glandularis (CG) is defined as glandular metaplasia of bladder urothelium. In most cases the course of CG is asymptomatic. However, some patients complain of hematuria and lower urinary tract symptoms (LUTS) of varying degrees. We present a case of 45-year-old man with an extensive CG causing acute urinary retention. Although it was initially treated as an infection, prompt ultrasound and cystoscopy helped to establish the diagnosis. Transurethral resection of the cyst with biopsy of the bladder mucosa was then performed. Immediately after surgery the patient noticed significant improvement in urine passing. During the 2-month follow-up there was no relapse.
    Central European Journal of Urology 06/2011; 64(2):94-6. DOI:10.5173/ceju.2011.02.art11