Psychiatric medications for the treatment of pruritus.

Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Palo Alto, CA 94305-5719, USA.
Psychosomatic Medicine (Impact Factor: 3.47). 01/2008; 69(9):970-8. DOI: 10.1097/PSY.0b013e3181572799
Source: PubMed


To review the use of psychiatric medications in the treatment of pruritus.
A literature review was conducted using the key words pruritus, psychiatric, and treatment.
Three categories of pruritus are described: dermatologic, systemic, and psychogenic. Peripheral and central nervous system mechanisms of pruritus are reviewed. Conventional dermatologic treatments for pruritus are contrasted with some of the common psychopharmacologic treatment modalities that include anxiolytic, antidepressant, and antipsychotic agents. A treatment algorithm is offered to help guide the treatment of patients with pruritus.
Psychiatric medications have been used successfully in the treatment of pruritus that is associated with both psychocutaneous and systemic disorders, which are resistant to conventional treatment.

Download full-text


Available from: Anna L Bruckner, Sep 29, 2014
  • [Show abstract] [Hide abstract]
    ABSTRACT: In this article a hybrid algorithm for model reference adaptive control of single-input single output systems is presented. The control structure involves a continuous time as well as a discrete time part, instead of being all discrete or all continuous as in previous approaches. The system is sampled periodically at a frequency F, and knowledge of bounds on the plant parameters enables us to determine a bound F* such that the closed loop system is stable whenever F > F*.
  • [Show abstract] [Hide abstract]
    ABSTRACT: Pruritus is an unpleasant sensation leading to the desire to scratch. It is the most common symptom in dermatology, and various skin and systemic diseases can be associated with the presence of itching. Pruritus may also be provoked by numerous drugs. Although the exact epidemiologic data are still absent, it is generally accepted that elderly people frequently suffer from pruritus, and the problem of itching in this population remains a challenge for clinicians. The elderly often complain of numerous comorbidities that complicate the determination of the cause of pruritus, as well as its treatment. Physical and mental deprivation may complicate proper assessment of pruritus severity and negatively impair compliance with complex antipruritic therapies. Taking also into account heterogeneity of possible causes of pruritus, every patient with pruritus must be handled individually, regarding the diagnostic procedures and antipruritic therapy.
    Clinics in dermatology 01/1995; 29(1):15-23. DOI:10.1016/j.clindermatol.2010.07.002 · 2.47 Impact Factor
  • [Show abstract] [Hide abstract]
    ABSTRACT: Among extra-dermatological itchings, psychogenic pruritus is sometimes provided as a diagnosis. Unfortunately, it is too often mislabeled as idiopathic pruritus because the patient is anxious or the doctor has no other diagnosis to propose! Think about the movie of Nani Morretti: “Caro diaro”…. The existence of psychogenic pruritus is sometimes discussed by some dermatologists but most of them agree to recognize psychogenic pruritus as a specific disease, which is cited in most reviews about pruritus. Nonetheless, only 31 papers with this key word were referenced by PubMed in July 2007!1 Regarding international classifications of psychiatric diseases, psychogenic pruritus is not cited in the (Inter-national Classification of Diseases-version 10) ICD-10 but pruritus is reported in the diagnosis termed “other somatoform disorders” (F45.8) along with dysmenorrhea, dysphagia, psychogenic stiff neck and bruxism. These disorders are classified among somatoform disorders, which are included in the broader category “neurotic disorders, stress-linked disorders and somatoform disorders.”
    12/2009: pages 223-227;
Show more