Onion and Garlic Intake and the Odds of Benign Prostatic Hyperplasia
University of Milan, Milano, Lombardy, Italy Urology
(Impact Factor: 2.19).
11/2007; 70(4):672-6. DOI: 10.1016/j.urology.2007.06.1099
To analyze the relationship between onion and garlic intake and benign prostatic hyperplasia (BPH), using data from a multicenter case-control study conducted in Italy.
A multicenter case-control study of 1369 patients with BPH and 1451 controls, admitted to the same hospitals for a wide spectrum of acute, non-neoplastic conditions, was conducted in Italy between 1991 and 2002. Information was collected by trained interviewers using a validated and reproducible food frequency questionnaire. Multivariate odds ratios (ORs) and 95% confidence intervals (CIs) were obtained after allowance for recognized confounding factors and energy intake.
Compared with nonusers, the multivariate ORs for the highest category of onion and garlic intake were 0.41 (95% CI 0.24 to 0.72) and 0.72 (95% CI 0.57 to 0.91), respectively. The combined OR for frequent users versus nonusers of both onion and garlic was 0.65 (95% CI 0.49 to 0.86). The inverse relationships were consistent across age strata.
This uniquely large data set from European populations showed an inverse association between allium vegetable consumption and BPH.
Available from: Jouko Vepsäläinen
- "In addition to their use in food preparation (Lanzotti, 2005), onions are also used for their therapeutic properties; they are active as diuretics and laxatives and against headaches and parasitic worms (Griffiths et al., 2002). Onion extracts have been reported to have beneficial properties against cancer (Galeone et al., 2007; Xiao and Parkin, 2007), cardiovascular diseases (Vazquez-Prieto and Miatello, 2010), blood pressure (Edwards et al., 2007) and inflammatory diseases (Tribolo et al., 2008). Onions are an important source of flavonoids, fructo-oligosaccharides (FOS), thiosulfinates and other sulfur compounds (Slimestad et al., 2007). "
[Show abstract] [Hide abstract]
ABSTRACT: Onions (Allium cepa L.) are an important source of bioactive compounds including flavonoids, fructo-oligosaccharides (FOS), thiosulfinates and other sulfur compounds, and many of these compounds have potential beneficial properties for human health. Onion metabolites have traditionally been analyzed separately using high-performance liquid chromatography (HPLC) and mass spectrometry (MS). However, it has recently been found that nuclear magnetic resonance (NMR) spectroscopy represents a powerful tool for the simultaneous analysis of a large number of compounds from plants. Although the NMR quantification method provides excellent quantification of compounds with separated spectral lines, the method often produces overlapping signals, and an improved quantification method is needed. Here, we used a constrained total-line-shape (CTLS) approach to quantify overlapping metabolites from onion proton nuclear magnetic resonance (1H NMR) spectra. This method permitted the identification and quantification of amino acids, organic acids, and sugars; however, aromatic compounds excluding aromatic amino acids were difficult to analyze by NMR spectroscopy because of the small signal intensities produced by flavonols and their sugar derivatives. Metabolites present at low concentrations were successfully analyzed using the developed mass spectrometry method operating in the positive mode. The 1H NMR method developed here is an efficient technique for use in simultaneously analyzing compounds in a food matrix.
Journal of Food Composition and Analysis 03/2012; 25:208-214. DOI:10.1016/j.jfca.2011.09.001 · 1.99 Impact Factor
Available from: kjurology.org
[Show abstract] [Hide abstract]
ABSTRACT: An inverse finite-element method for the design of nonlinear
magnetic devices is presented. The objective of applying the
finite-element method in an inverse manner is to yield the optimum
geometry while maintaining the operating performance requirements of the
device. A nonlinear iron-cored inductance coil, which involves a
relatively complex magnetic circuit topology, was used as an application
of the method. Several design problems in which certain output
quantities are specified, while the geometry was determined by the
inverse procedure have been studied. The results were verified using
standard finite-element programs, and were found to be in complete
Southeastcon '88., IEEE Conference Proceedings; 05/1988
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.