Effects of child formula dentifrices on artificial caries like lesions using in vitro pH-cycling: preliminary results.
ABSTRACT To compare the remineralisation effects of different child dentifrices on primary teeth.
In vitro single-section technique and pH-cycling model.
Primary teeth were painted with nail varnish, leaving a 1 mm wide window before placing in demineralising solution for 96hr to produce artificial carious lesions 150-200 microm deep. Teeth were longitudinally cut into approximately 100-150 microm thick sections and assigned to three groups (n = 7). Sections in Group A were exposed to Perioe Children's Toothpaste (LG, Korea), Group B to Colgate Pokemon (Colgate-Palmolive, Thailand) and Group C to Vicco (Vicco Laboratories, India). Polarised light microscopy and microradiography was used to evaluate lesion depth, before and after 7 days pH cycle.
Mean lesion depths in Groups A and C increased by 11% and 14% respectively, while Group B demonstrated a lesion reduction of 3%. Comparisons using ANOVA and Student-Newman-Keuls tests showed that Groups A and C were significantly different from Group B (p < 0.05), but there was no significant difference between Groups A and C.
Based on the data obtained, Colgate Pokemon remineralised initial carious lesions. In addition, when compared to Colgate Pokemon, Perioe Children's Toothpaste failed to show 'healing' efficacy even though it is claimed to contain fluoride.
SourceAvailable from: Manikandan Ekambaram[Show abstract] [Hide abstract]
ABSTRACT: The ADA recommends the use of fluoridated dentifrices as soon as the primary teeth erupt, so as to reduce the incidence of dental caries. However young children can ingest a significant amount of dentifrice during normal toothbrushing; this is a potential problem because the permanent teeth are at risk from fluorosis for the first seven years of life. the objective of this paper was to review the literature on the role of fluoride dentifrices in causing dental fluorosis. Search strategy: a search for literature was performed using MEDLINE, OVID with the key words fluorosis, dentifrice, ingestion, and children. The search was limited to English language publications. Subsequently, 31 articles were retrieved, additional relevant articles were collected from the references cited in the initially identified papers. Ultimately, 96 articles were retrieved for review. Fluoride, should be used with caution so that the benefits out-way the adverse affects. Oral health care providers need to systematically assess individual tooth brushing habits and emphasize the advantages of early use of a fluoridated dentifrice whilst still meeting the need for the prudent use of small quantities of dentifrice. Dentifrices with a low concentration of fluoride may be appropriate for young children who are considered to be at low caries risk and the risk of fluorosis is minimal for children who ingest this dentifrice; nevertheless, it appears that more research is still required on the therapeutic effects of fluoride dentifrices which contain fluoride at a low concentration.The Journal of clinical pediatric dentistry 01/2011; 36(2):111-21. · 0.34 Impact Factor
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ABSTRACT: Aim: To evaluate the remineralizing potential of child formula dentifrices on primary teeth using an in vitro 7 days pH cycling model. Materials and Methods: Twenty‑one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100–150 μm thick sections and randomly assigned to three groups. Sections in Group A were treated with dentifrice containing 458 ppm monofluorophosphate (MFP) and sections in Group B with 500 ppm sodium fluoride (NaF). Group C sections were treated with a nonfluoridated dentifrice. Results: Group A (458 ppm MFP) and Group B (500 ppm NaF) showed significant decrease in lesion depth, whereas Group C (non F) showed a significant increase in depth (P ≤ 0.05, paired t‑test). Conclusion: Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstratedremineralization of carious lesions, it was not complete. Therefore, it is also important to emphasize on other preventive methodsin the prevention and/or reversal of carious lesions. Keywords: Artificial caries, fluoride dentifrices, pH cycling, primary teeth
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ABSTRACT: The aim of the following study is to know the efficacy of remineralization of two pediatric dentifrices and one regular dentifrice on artificial carious lesions in primary teeth.05/2014; 4(2):96-102. DOI:10.4103/2231-0762.137627