Article

Chronic lymphocytic leukaemia genetics overview.

Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
British Journal of Haematology (Impact Factor: 4.94). 01/2008; 139(5):630-4. DOI: 10.1111/j.1365-2141.2007.06846.x
Source: PubMed

ABSTRACT Although the familial aspect of chronic lymphocytic leukaemia (CLL) has been appreciated for decades, it is only with the recent confluence of improved molecular and gene technologies and world-wide collaborative networks that accelerated progress has become apparent. In this summary we highlight selected themes in the genetics of CLL emphasizing the opportunities and challenges of this malignancy.

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