Adequacy and pattern of blood donations in north-eastern Nigeria: the implications for blood safety.
ABSTRACT In a retrospective analysis, the quantities, patterns and adequacy of blood donations made, between 1984 and 2006, at the University of Maiduguri Teaching Hospital in north-eastern Nigeria were explored and related to blood safety in the study area. The types of blood donor were reviewed and the annual increments in the number of donations made were estimated and compared with the annual increments in the numbers of in-patients managed at the study hospital. The mean annual increment in the number of blood donations (4%) fell well below the mean annual increment in in-patient numbers (11%). The blood donations received at the hospital fell into four types: voluntary, family-replacement, commercial and pre-deposit autologous donations. Over the study period, the percentage of donations falling into the voluntary and family-replacement categories fell from 31% to 5% and from 49% to 23%, respectively. These falls were matched by increases in the percentages of donations categorised as commercial and autologous, which rose from 20% to 63%, and from 1% to 9%, respectively. By the end of the study period, the quantity of blood being donated at the hospital was grossly inadequate and predominantly derived from family and commercial donors, who were found to be generally inferior, in terms of blood safety, to voluntary donors. There is an urgent need to rectify this situation by setting up a functional and national blood-transfusion service in Nigeria.
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ABSTRACT: Background: Blood donation is generally inadequate in Nigeria. Kano state is the most populous state in northern Nigeria where agriculture is a major occupation. Hence, we hypothesized that blood donations would be lower during rainy season as eligible donors become more engrossed in farming activities that distract them from blood donation. Materials and Methods: Accordingly, we retrospectively studied the amount of blood donations at Aminu Kano Teaching Hospital in Kano, northern Nigeria (2009 to 2012). Results: Data analysis using Chi square test revealed significantly lower mean number of monthly donations during rainy seasons (Mean + SD: 587.2+15) in comparison to dry seasons (Mean + SD: 693.4+18), p<0.05. Conclusion: There is therefore the need to offset this seasonal shortfall in blood donations, and its potentially adverse implications on health care, by intensifying community enlightenment in order to boost blood donations during the rainy season.Annals of Tropical Pathology. 01/2013; 4(2):77-82.
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ABSTRACT: Anaemic donors in Nigeria are often empirically treated with haematinics without investigations. We studied morphological pattern of anaemia among first-time donors in Kano, Nigeria and reviewed the clinical implications of empirical use of haematinics with respect to morphology. Haematological parameters of 182 first-time prospective blood donors with anaemia were determined and morphological classification of the anaemias were undertaken based on red cell indices. Out of 182 anaemic donors, 56.6% had microcytic hypochromic anaemia, 19.2% had macrocytic anaemia, 17.6% had dimorphic anaemia and 6.6% had normocytic normochromic anaemia. The heterogeneous pattern of morphological classes of anaemia was indicative of diverse aetiological factors, hence empirical therapy with haematinics may ineffective or hazardous in many cases of anaemia among first-time blood donors in Nigeria. It is therefore necessary for blood banks in Nigeria to have standard guidelines for investigating anaemic donors before embarking on therapy.International Journal of Biomedical and Health Sciences. 01/2011; 7(2):125-129.
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ABSTRACT: Introduction. Hypertransfusion refers to chronic blood transfusion therapy aimed at ameliorating disease complications in various haemopathies particularly the haemoglobinopathies. In sickle cell disease, hypertransfusion is aimed at maintaining patient's haemoglobin level at 10 to 11 g/dL using haemoglobin AA blood and its resultant dilutional effect on sickle haemoglobin is sustained by intermittent long-term transfusions. Aim and Objective. This paper highlights hypertransfusion and its privileged position as a secondary measure in prevention and treatment of sickle cell disease, especially in the Nigerian context. Materials and Methods. Relevant literatures were searched on PubMed, Google Scholar and standard texts in haematology and transfusion medicine. Keywords used in the search are hypertransfusion, sickle cell disease, chronic transfusion, and Nigeria. Literatures gathered were reviewed, summarized, and presented in this paper. Result. Immense clinical benefit is associated with hypertransfusion therapy including prevention of stroke and amelioration of severe sickle cell disease especially in transplant ineligible patients. Careful patient selections, appropriate blood component, and prevention of transfusion hazards as well as oversight function of an experienced haematologist are pertinent to a successful hypertransfusion therapy. Conclusion. Improved knowledge of the benefits and practice of hypertransfusion will effectively translate into improved health status even among Nigerian sickle cell disease patients.Advances in Hematology 01/2014; 2014:923593.