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Ectodermal dysplasia with alopecia, onychodysplasia, hypohidrosis, keratoderma, abnormal teeth and deafness.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Indian journal of dermatology, venereology and leprology (Impact Factor: 1.33). 01/2007; 73(6):409-11. DOI: 10.4103/0378-6323.37060
Source: PubMed

ABSTRACT The ectodermal dysplasias are a heterogeneous group of disorders with primary defect in hair, teeth, nail and sweat gland function. Numerous types have been described and several classifications exist. Here, we present a patient with ectodermal dysplasia with alopecia, dysplastic nails, hypohidrosis, sensorineural deafness, palmoplantar keratoderma, abnormal teeth and dry skin. To our knowledge, combination of all these features in ectodermal dysplasia has not been reported in the past. The etiology is unknown, but consanguinity of parents points to an autosomal recessive inheritance.

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