Polyuria and polydipsia in horses.

Clinical Sciences Department, College of Veterinary Medicine, Oregon State University, 227 Magruder Hall, Corvallis, OR 97331, USA.
The Veterinary clinics of North America. Equine practice (Impact Factor: 0.79). 01/2008; 23(3):641-53, vii. DOI: 10.1016/j.cveq.2007.08.001
Source: PubMed

ABSTRACT Polyuria and polydipsia provide a diagnostic challenge for the equine clinician. This article describes the various known causes of polyuria and polydipsia in horses and provides a description of a systematic diagnostic approach for assessing horses with polyuria and polydipsia to delineate the underlying cause. Treatment and management strategies for addressing polyuria and polydipsia in horses are also described.

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    ABSTRACT: Central diabetes insipidus (DI) was diagnosed in a 20-year-old American Quarter Horse gelding that was concomitantly affected with pituitary pars intermedia dysfunction (PPID). The diagnosis of DI was supported by a positive response to administered desmopressin acetate. Diagnosis of PPID was supported by physical appearance and elevated plasma adrenocorticotropic hormone concentration following domperidone administration. The horse's physical condition improved following treatment with pergolide but long-term treatment with desmopressin was not undertaken and severe polyuria and polydipsia persisted. Desmopressin acetate appears to be useful for the diagnosis of DI in mature horses concomitantly affected with PPID.
    03/2013; 25(3). DOI:10.1111/j.2042-3292.2011.00377.x

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