Article

Direct cost burden among insured US employees with migraine.

IMS Health, Brooklyn, MI, USA.
Headache The Journal of Head and Face Pain (impact factor: 2.52). 05/2008; 48(4):553-63. DOI:10.1111/j.1526-4610.2007.00990.x
Source: PubMed

ABSTRACT To provide a current estimate of the national direct health-care cost burden of illness associated with migraine among a US insured population.
Individuals with migraine use health-care resources more than those without migraine, incurring substantial costs to US employers.
The Thomson Medstat's Commercial Claims and Encounters 2004 database was utilized for this study. Only paid claims were analyzed. The migraine cohort had a primary migraine diagnosis and/or a migraine-specific abortive drug prescription during 2004. A matched control cohort with no evidence of migraine was generated using propensity score techniques. Demographic characteristics and overall comorbidities were similar between cohorts. A second-stage regression controlled for any remaining significant intergroup differences. The burden of illness of migraine was defined as the difference in average total health-care expenditures per person between cohorts. The national burden of illness was defined as the average expenditure for migraine of national population estimates of privately insured individuals, and was estimated by projecting the migraine prevalence rate and average expenditure using Medical Expenditure Panel Survey population estimates.
Patients with migraine (n=215,209) had significantly higher average health-care expenditures compared with matched controls ($7007 vs $4436 per person per year; difference of $2571; P<.001). Migraine-associated national expenditure estimates: outpatient care, $5.21 billion; prescriptions, $4.61 billion; inpatient care, $0.73 billion; and emergency department care, $0.52 billion.
The direct costs associated with patients with migraine were found to be $2571 per person per year higher than in matched nonmigraine controls. The projected national burden of migraine of $11.07 billion is substantially higher than previous estimates.

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Keywords

average expenditure
 
average total health-care expenditures
 
Demographic characteristics
 
emergency department care
 
Encounters 2004 database
 
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inpatient care
 
matched control cohort
 
migraine cohort
 
migraine prevalence rate
 
migraine use health-care resources
 
migraine-specific abortive drug prescription
 
national burden
 
national direct health-care cost burden
 
national population estimates
 
outpatient care
 
primary migraine diagnosis
 
projected national burden
 
significant intergroup differences
 
Thomson Medstat's Commercial Claims