Successful use of etanercept in the treatment of acute lupus hemophagocytic syndrome.
ABSTRACT Hemophagocytic syndrome has been reported to be associated with systemic lupus erythematosus. A 25-year-old woman with systemic lupus erythematosus developed hemophagocytic syndrome that was refractory to the combination therapy with high-dose corticosteroid, cyclosporine, and high-dose intravenous immunoglobulin, and successfully treated with the tumor necrosis factor inhibitor, etanercept. This case report provided the first observation that etanercept may be useful for the treatment of hemophagocytic syndrome associated with systemic lupus erythematosus refractory to conventional therapy.
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ABSTRACT: Over the last few decades, the use of sigma-delta (Σ-Δ) modulators has moved into mainstream applications in signal processing such as A/D, D/A, and communication. Σ-Δ modulators produce a single, or few, bit output, making them suitable for realization in VLSI circuits. For improved signal-to-quantization-noise ratio, higher order modulators, such as multi-loop and multi-stage architectures, are commonly used. The quantization noise behavior of these higher order modulators is well understood. Based on these quantization noise characteristics, various demodulator architectures, such as optimal FIR filter, sinc filter, and Laguerre filter are reported in the literature. An efficient FPGA (field programmable gate array) implementation of a Kalman recursive low-pass filter suitable for application in Σ-Δ demodulation is reported. FPGA synthesis results, as well as filter performance, as compared to previous designs for sinc filters and Laguerre filters, are given.Signal Processing Systems, 2003. SIPS 2003. IEEE Workshop on; 09/2003
Conference Paper: Ensuring information assurance in federated identity management[Show abstract] [Hide abstract]
ABSTRACT: Surveys and polling data confirm that the Internet is now a prime vehicle for business, community, and personal interactions. The notion of identity is the important component of this vehicle. When users interact with services on the Internet, they often tailor the services in some way for their personal use. For example, a user may establish an account with a username and password and/or set some preferences for what information the user wants displayed and how the user wants it displayed. The network identity of each user is the overall global set of these attributes constituting the various accounts. In this paper, we investigate two well-known federated identity management (FIM) solutions, Microsoft Passport and Liberty Alliance, attempting to identify information assurance (IA) requirements in FIM. In particular, we focus on principal IA requirements for Web services (WS) which plays an integral role in enriching identity management through federation.Performance, Computing, and Communications, 2004 IEEE International Conference on; 02/2004
- Lupus 02/2009; 18(1):5-8. DOI:10.1177/0961203308098190 · 2.48 Impact Factor