Article

Treatment of infected hip arthroplasty with antibiotic-impregnated calcium hydroxyapatite.

Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Mie, Japan.
The Journal of Arthroplasty (impact factor: 2.38). 02/2008; 23(1):145-50. DOI:10.1016/j.arth.2006.09.009 pp.145-50
Source: PubMed

ABSTRACT We reviewed the treatment of infected hip arthroplasty with antibiotic-impregnated calcium hydroxyapatite (CHA) ceramic blocks. Seven consecutive patients consisting of 2 men and 5 women with an average age of 65 years were followed up for an average of 5.0 years. All patients received resection arthroplasty and thorough debridement, followed by implantation of antibiotic-impregnated CHA ceramic. Two-stage revision was performed in all patients. There was no evidence of a recurrent infection in 6 patients. The remaining one patient underwent an additional debridement 2 years after the second stage. This patient was free of infection at the time of the latest follow-up. Antibiotic-impregnated CHA ceramic is thus considered to be an excellent drug delivery system for the infected hip arthroplasty.

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Keywords

2 men
 
5 women
 
6 patients
 
additional debridement 2 years
 
antibiotic-impregnated calcium hydroxyapatite
 
consecutive patients
 
excellent drug delivery system
 
hip arthroplasty
 
infected hip arthroplasty
 
latest follow-up
 
patients
 
remaining one patient
 
resection arthroplasty
 
second stage
 
thorough debridement