Bilateral Paget disease of the male nipple: first report.

General Surgery Department, Ankara Ataturk Teaching and Research Hospital, Askaabat Cad. Eser Sitesi B3 Blok Daire:11, Bahcelievler, Ankara 06480, Turkey.
The Breast (Impact Factor: 2.49). 07/2008; 17(3):317-8. DOI: 10.1016/j.breast.2007.11.007
Source: PubMed

ABSTRACT Bilateral breast carcinoma is reported to occur in 5-10% of all patients with breast cancer. Paget disease of the breast represents 1-3% of all breast malignancies [Ashikari R, Park K, Huvos AG, Urban JA. Paget's disease of the breast. Cancer 1970;26:680-5; Marshall JK, Griffith KA, Haffty BG, Solin LJ, Vicini FA, McCormick B, et al. Conservative management of Paget disease of the breast with radiotherapy. Cancer 2003;97:2142-9]. However, synchronous bilateral Paget disease of the nipple is extremely rare. We report synchronous bilateral Paget disease with infiltrative ductal carcinoma in a 74-year-old man who underwent bilateral mastectomy.

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    ABSTRACT: Vorgestellt wird eine 71-jährige Patientin mit ekzematösen, therapierefraktären Hautveränderungen beider Mamillae seit 2,5 Jahren. Trotz intensiver gynäkologisch/radiologischer Abklärung konnten keine Auffälligkeiten festgestellt werden. Durch die operative Versorgung des beidseits durch Biopsie diagnostizierten M. Paget wurden jedoch duktale Karzinome (DCIS) bestätigt. Insbesondere bei therapierefraktären Hautbefunden der Mamille sollte die Indikation zur Biopsie großzügig gestellt werden. Bestätigt sich die Verdachtsdiagnose M. Paget, ist die operative Versorgung auch zum Ausschluss ursächlicher duktaler Karzinome unverzichtbar.
    Der Gynäkologe 46(2).
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    ABSTRACT: Paget's disease of the breast is often misdiagnosed. We report on a 72-year old patient with a history of 2.5 years without any malignant findings, followed by the identification of a bilateral Paget's disease with bilateral breast cancers. This case underlines how important histological examinations even in unusual clinical pictures are.
    Case reports in dermatological medicine. 01/2014; 2014:152836.
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    ABSTRACT: Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. Male breast cancer represents only 1-3% of all breast malignancies and Paget's disease remains very rare. We present the case of a 67-year-old Caucasian man with lymphomatoid papulosis who was diagnosed with Paget's disease of the nipple and who was treated successfully with surgery alone. We discuss the presentation, investigations, management and pathogenesis of Paget's disease of the nipple. The case highlights the need to be vigilant when new skin lesions arise in the context of an underlying chronic skin disorder.
    Journal of Medical Case Reports 01/2011; 5:43.